MR features of small hepatocellular carcinoma in normal, fibrotic, and cirrhotic livers: a comparative study
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| 024 | 7 | 0 | |a 10.1007/s00261-015-0536-3 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-015-0536-3 | ||
| 245 | 0 | 0 | |a MR features of small hepatocellular carcinoma in normal, fibrotic, and cirrhotic livers: a comparative study |h [Elektronische Daten] |c [Ruo Sheng, Meng Zeng, Yuan Ji, Li Yang, Cai Chen, Sheng Rao] |
| 520 | 3 | |a Purpose: The objective of this study is to compare MR imaging features of small hepatocellular carcinoma (HCC) (≤2cm) in normal, fibrotic, and cirrhotic liver. Methods: A total of 215 patients with 235 pathologically proven sHCC were retrospectively analyzed. Patients were classified into three groups according to the patients' liver condition: patients with normal liver (F0, group 1), fibrosis without cirrhosis (F1-3, group 2), and cirrhosis (F4, group 3). The morphological and MR signal features on T1, T2-weighted, dynamic enhanced, and diffusion-weighted imaging were evaluated and compared. Results: There were 10, 38, and 167 patients in group 1, 2, and 3, respectively. Patients with normal liver were older than those with fibrosis or cirrhosis (P=0.0086), and tumors in the normal liver were larger than those in the fibrotic or cirrhotic liver (P=0.0407). No statistical differences were found among groups in signals on T2-weighted images (P=0.163), signals on each phase after contrast (P=0.269, 0.893, and 0.259, respectively), enhancement patterns (P=0.753), ADC values (P=0.760), as well as the presence of capsule-like enhancement (P=0.953), mosaic pattern (P=0.572), fat content (P=0.222), iron sparing (P=1.000), hemorrhage (P=0.181), and venous invasion (P=0.175). Both signal-to-noise ratios (SNR) (χ 2=2.045, P=0.132) and lesion-to-liver contrast-to-noise ratios (CNR) (χ 2=0.438, P=0.646) were not different as well. But confusing features of iso/hypointensity on T2-weighted imaging (n=11, 6.0%) and progressive enhancement pattern (n=2, 1.1%) were exclusively found in the cirrhosis background, and hypovascular tumors with iso/hypointensity on arterial phase were only seen in the fibrosis (n=5, 11.9%) and cirrhosis groups (n=10, 5.5%). Conclusion: MR features of sHCC were similar among patients with normal, fibrotic, and cirrhotic livers. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Hepatocellular carcinoma |2 nationallicence | |
| 690 | 7 | |a Cirrhosis |2 nationallicence | |
| 690 | 7 | |a Fibrosis |2 nationallicence | |
| 690 | 7 | |a Magnetic resonance imaging |2 nationallicence | |
| 700 | 1 | |a Sheng |D Ruo |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | |
| 700 | 1 | |a Zeng |D Meng |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | |
| 700 | 1 | |a Ji |D Yuan |u Department of Pathology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | |
| 700 | 1 | |a Yang |D Li |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | |
| 700 | 1 | |a Chen |D Cai |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | |
| 700 | 1 | |a Rao |D Sheng |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/8(2015-10-01), 3062-3069 |x 0942-8925 |q 40:8<3062 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-015-0536-3 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-015-0536-3 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sheng |D Ruo |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zeng |D Meng |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ji |D Yuan |u Department of Pathology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yang |D Li |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chen |D Cai |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Rao |D Sheng |u Department of Radiology, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, 200032, Shanghai, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/8(2015-10-01), 3062-3069 |x 0942-8925 |q 40:8<3062 |1 2015 |2 40 |o 261 | ||