caa a22 4500 605494967 CHVBK 20210128100529.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00261-014-0266-y doi (NATIONALLICENCE)springer-10.1007/s00261-014-0266-y Metabolic signatures of malignant and non-malignant mass-forming lesions in the periampulla and pancreas in FDG PET/CT scan: an atlas with pathologic correlation [Elektronische Daten] [Sampath Santhosh, Bhagwant Mittal, Surinder Rana, Radhika Srinivasan, Anish Bhattacharya, Ashim Das, Deepak Bhasin] Positron emission tomography (PET) has been used for the characterization of pancreatic and periampullary lesions. Pancreatitis-associated inflammation affecting only a portion of the pancreas gives the appearance of a mass lesion on imaging. Consequently, the differential diagnosis between cancer and pancreatitis becomes a commonly encountered problem. Traditionally, PET was interpreted as positive (to denote malignancy) if fluorodeoxyglucose (FDG) activity in the pancreas exceeded background activity and as negative (to denote benign) if activity was less than or equal to background activity. However, the specificity was limited with this method of interpretation. A relatively wide overlap has been reported between semiquantitative uptake values obtained in cancers and those in inflammatory lesions. Also, the qualitative (metabolic patterns) and quantitative variables (standardized uptake values) have been complementary and at sometimes controversial to each other in various clinical situations. There is paucity of data in the literature highlighting the role of FDG PET/CT in characterization of such mass lesions. The primary aim of this pictorial review is to list the various pathologic processes of pancreas and periampulla that could be studied with FDG PET/CT and recognize the different FDG uptake patterns and apply this information to characterize the different lesions affecting the pancreas and periampulla. We have also discussed the limitations of conventional imaging and advantages of FDG PET/CT for the evaluation mass-forming lesions of the pancreas and periampulla. Springer Science+Business Media New York, 2014 Pancreatic adenocarcinoma nationallicence Periampullary adenocarcinoma nationallicence Maltoma nationallicence Autoimmune pancreatitis nationallicence Lymphoma nationallicence FDG PET/CT nationallicence Santhosh Sampath Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Mittal Bhagwant Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Rana Surinder Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Srinivasan Radhika Department of Cytology and Gynaecological Pathology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Bhattacharya Anish Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Das Ashim Department of Histopathology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Bhasin Deepak Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1285-1315 0942-8925 40:5<1285 2015 40 261 https://doi.org/10.1007/s00261-014-0266-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0266-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Santhosh Sampath Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Mittal Bhagwant Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Rana Surinder Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Srinivasan Radhika Department of Cytology and Gynaecological Pathology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Bhattacharya Anish Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Das Ashim Department of Histopathology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Bhasin Deepak Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1285-1315 0942-8925 40:5<1285 2015 40 261