caa a22 4500 605494983 CHVBK 20210128100529.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00261-014-0264-0 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0264-0 Half-dose non-contrast CT in the investigation of urolithiasis: image quality improvement with third-generation integrated circuit CT detectors [Elektronische Daten] [Jun Wang, Tony Kang, Chesnal Arepalli, Sarah Barrett, Tim O'Connell, Luck Louis, Savvakis Nicolaou, Patrick McLaughlin] Purpose: The objective of this study is to establish the effect of third-generation integrated circuit (IC) CT detector on objective image quality in full- and half-dose non-contrast CT of the urinary tract. Methods: 51 consecutive patients with acute renal colic underwent non-contrast CT of the urinary tract using a 128-slice dual-source CT before (n=24) and after (n=27) the installation of third-generation IC detectors. Half-dose images were generated using projections from detector A using the dual-source RAW data. Objective image noise in the liver, spleen, right renal cortex, and right psoas muscle was compared between DC and IC cohorts for full-dose and half-dose images reconstructed with FBP and IR algorithms using 1cm2 regions of interest. Presence and size of obstructing ureteric calculi were also compared for full-dose and half-dose reconstructions using DC and IC detectors. Results: No statistical difference in age and lateral body size was found between patients in the IC and DC cohorts. Radiation dose, as measured by size-specific dose estimates, did not differ significantly either between the two cohorts (10.02±4.54mGy IC vs. 12.28±7.03mGy DC). At full dose, objective image noise was not significantly lower in the IC cohort as compared to the DC cohort for the liver, spleen, and right psoas muscle. At half dose, objective image noise was lower in the IC cohort as compared to DC cohort at the liver (21.32 IC vs. 24.99 DC, 14.7% decrease, p<0.001), spleen (19.33 IC vs. 20.83 DC, 7.20% decrease, p=0.02), and right renal cortex (20.28 IC vs. 22.98 DC, 11.7% decrease, p=0.005). Mean obstructing ureteric calculi size was not significantly different when comparison was made between full-dose and half-dose images, regardless of detector type (p>0.05 for all comparisons). Conclusions: Third-generation IC detectors result in lower objective image noise at full- and half-radiation dose levels as compared with traditional DC detectors. The magnitude of noise reduction was greater at half-radiation dose indicating that the benefits of using novel IC detectors are greater in low and ultra-low-dose CT imaging. Springer Science+Business Media New York, 2014 Computed tomography (CT) nationallicence Integrated circuit (IC) nationallicence Dose reduction nationallicence Urinary calculi nationallicence Wang Jun Faculty of Medicine, University of British Columbia, V5Z 1M9, Vancouver, Canada aut Kang Tony Faculty of Medicine, University of British Columbia, V5Z 1M9, Vancouver, Canada aut Arepalli Chesnal Faculty of Medicine, University of British Columbia, V5Z 1M9, Vancouver, Canada aut Barrett Sarah Faculty of Medicine, University of British Columbia, V5Z 1M9, Vancouver, Canada aut O'Connell Tim ER Radiology Division, Department of Radiology, Vancouver General Hospital, 899W 12th Ave., V5Z 1M9, Vancouver, BC, Canada aut Louis Luck ER Radiology Division, Department of Radiology, Vancouver General Hospital, 899W 12th Ave., V5Z 1M9, Vancouver, BC, Canada aut Nicolaou Savvakis ER Radiology Division, Department of Radiology, Vancouver General Hospital, 899W 12th Ave., V5Z 1M9, Vancouver, BC, Canada aut McLaughlin Patrick ER Radiology Division, Department of Radiology, Vancouver General Hospital, 899W 12th Ave., V5Z 1M9, Vancouver, BC, Canada aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1255-1262 0942-8925 40:5<1255 2015 40 261 https://doi.org/10.1007/s00261-014-0264-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0264-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Jun Faculty of Medicine, University of British Columbia, V5Z 1M9, Vancouver, Canada aut NATIONALLICENCE 700 1- Kang Tony Faculty of Medicine, University of British Columbia, V5Z 1M9, Vancouver, Canada aut NATIONALLICENCE 700 1- Arepalli Chesnal Faculty of Medicine, University of British Columbia, V5Z 1M9, Vancouver, Canada aut NATIONALLICENCE 700 1- Barrett Sarah Faculty of Medicine, University of British Columbia, V5Z 1M9, Vancouver, Canada aut NATIONALLICENCE 700 1- O'Connell Tim ER Radiology Division, Department of Radiology, Vancouver General Hospital, 899W 12th Ave., V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- Louis Luck ER Radiology Division, Department of Radiology, Vancouver General Hospital, 899W 12th Ave., V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- Nicolaou Savvakis ER Radiology Division, Department of Radiology, Vancouver General Hospital, 899W 12th Ave., V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- McLaughlin Patrick ER Radiology Division, Department of Radiology, Vancouver General Hospital, 899W 12th Ave., V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1255-1262 0942-8925 40:5<1255 2015 40 261