Differentiation of Malignant Omental Caking from Benign Omental Thickening using MRI

Verfasser / Beitragende:
[Ankur Doshi, Naomi Campbell, Cristina Hajdu, Andrew Rosenkrantz]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/5(2015-06-01), 1157-1163
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0259-x  |2 doi 
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245 0 0 |a Differentiation of Malignant Omental Caking from Benign Omental Thickening using MRI  |h [Elektronische Daten]  |c [Ankur Doshi, Naomi Campbell, Cristina Hajdu, Andrew Rosenkrantz] 
520 3 |a Purpose: To determine multi-parametric MRI features that can help differentiate malignant omental caking from benign omental thickening in the setting of portal hypertension. Methods: We identified 19 patients with an abnormal omentum on MRI and an available reference standard: 11 patients with portal hypertension and benign omental thickening (9 male, 2 female, mean age 58±6years) and 8 patients with metastatic omental caking (4 male, 4 female, mean age 61±13years). Criteria for benign omental thickening were no evidence of malignancy for at least 24months of follow-up (n=7), negative ascites cytology (n=2), or absence of malignancy on pathologic analysis of liver explant (n=2). Criteria for omental malignancy were positive omental biopsy (n=6) or ascites cytology (n=2). Two radiologists (R1 and R2) evaluated characteristics of the thickened omentum on MRI. Results: Findings occurring with significantly higher frequency in malignant omental caking were hyperintensity on high b-value diffusion-weighted imaging (DWI) (R1 88% vs. 0%, R2 88% vs. 0%), hyperenhancement (R1 75% vs. 0%, R2 75% vs. 0%), and convex outer omental contour (R1 88% vs. 0%, R2 75% vs. 9%) (all p≤0.001); discrete omental nodules were significantly more frequent in malignant omental thickening for R1 (63% vs. 0%, p=0.005). Features not significantly different between groups included decreased ADC, T2 hyperintensity, vessels coursing through the omentum, moderate/large volume ascites, splenomegaly, and mesenteric edema (all p≥0.058). Conclusion: Abnormal signal on DWI, hyperenhancement, and convex outer contour are helpful MRI features to differentiate malignant from benign omental thickening. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Cirrhosis  |2 nationallicence 
690 7 |a Omental caking  |2 nationallicence 
690 7 |a Portal hypertension  |2 nationallicence 
690 7 |a Peritoneal carcinomatosis  |2 nationallicence 
700 1 |a Doshi  |D Ankur  |u Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
700 1 |a Campbell  |D Naomi  |u Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
700 1 |a Hajdu  |D Cristina  |u Department of Pathology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
700 1 |a Rosenkrantz  |D Andrew  |u Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/5(2015-06-01), 1157-1163  |x 0942-8925  |q 40:5<1157  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0259-x  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0259-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Doshi  |D Ankur  |u Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Campbell  |D Naomi  |u Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hajdu  |D Cristina  |u Department of Pathology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Rosenkrantz  |D Andrew  |u Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/5(2015-06-01), 1157-1163  |x 0942-8925  |q 40:5<1157  |1 2015  |2 40  |o 261