caa a22 4500 605495068 CHVBK 20210128100529.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00261-014-0259-x doi (NATIONALLICENCE)springer-10.1007/s00261-014-0259-x Differentiation of Malignant Omental Caking from Benign Omental Thickening using MRI [Elektronische Daten] [Ankur Doshi, Naomi Campbell, Cristina Hajdu, Andrew Rosenkrantz] Purpose: To determine multi-parametric MRI features that can help differentiate malignant omental caking from benign omental thickening in the setting of portal hypertension. Methods: We identified 19 patients with an abnormal omentum on MRI and an available reference standard: 11 patients with portal hypertension and benign omental thickening (9 male, 2 female, mean age 58±6years) and 8 patients with metastatic omental caking (4 male, 4 female, mean age 61±13years). Criteria for benign omental thickening were no evidence of malignancy for at least 24months of follow-up (n=7), negative ascites cytology (n=2), or absence of malignancy on pathologic analysis of liver explant (n=2). Criteria for omental malignancy were positive omental biopsy (n=6) or ascites cytology (n=2). Two radiologists (R1 and R2) evaluated characteristics of the thickened omentum on MRI. Results: Findings occurring with significantly higher frequency in malignant omental caking were hyperintensity on high b-value diffusion-weighted imaging (DWI) (R1 88% vs. 0%, R2 88% vs. 0%), hyperenhancement (R1 75% vs. 0%, R2 75% vs. 0%), and convex outer omental contour (R1 88% vs. 0%, R2 75% vs. 9%) (all p≤0.001); discrete omental nodules were significantly more frequent in malignant omental thickening for R1 (63% vs. 0%, p=0.005). Features not significantly different between groups included decreased ADC, T2 hyperintensity, vessels coursing through the omentum, moderate/large volume ascites, splenomegaly, and mesenteric edema (all p≥0.058). Conclusion: Abnormal signal on DWI, hyperenhancement, and convex outer contour are helpful MRI features to differentiate malignant from benign omental thickening. Springer Science+Business Media New York, 2014 Cirrhosis nationallicence Omental caking nationallicence Portal hypertension nationallicence Peritoneal carcinomatosis nationallicence Doshi Ankur Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Campbell Naomi Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Hajdu Cristina Department of Pathology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Rosenkrantz Andrew Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1157-1163 0942-8925 40:5<1157 2015 40 261 https://doi.org/10.1007/s00261-014-0259-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0259-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Doshi Ankur Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Campbell Naomi Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Hajdu Cristina Department of Pathology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Rosenkrantz Andrew Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1157-1163 0942-8925 40:5<1157 2015 40 261