caa a22 4500 605495076 CHVBK 20210128100529.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00261-014-0258-y doi (NATIONALLICENCE)springer-10.1007/s00261-014-0258-y Identifying decreased peristalsis of abnormal small bowel segments in Crohn's disease using cine MR enterography: the frozen bowel sign [Elektronische Daten] [Flavius Guglielmo, Donald Mitchell, Patrick O'Kane, Sandeep Deshmukh, Christopher Roth, Ilene Burach, Aaron Burns, Susan Dulka, Laurence Parker] Purpose: The purpose of this study was to evaluate whether affected bowel in Crohn's disease patients can be identified by observing decreased peristalsis (frozen bowel sign) using cine balanced steady-state free precession (cine BSSFP) images. Materials and methods: 5 radiologists independently reviewed cine BSSFP sequences from randomized MR Enterography (MRE) exams for 30 normal and 30 Crohn's disease patients, graded overall small bowel peristalsis from slowest to fastest, and graded peristalsis for the most abnormal small bowel segment. Sensitivity and specificity of the frozen bowel sign for diagnosing Crohn's disease were calculated. T tests of the peristalsis difference between abnormal segments and overall small bowel were conducted. Results: For 5 readers, the sensitivity and specificity of cine BSSFP of the frozen bowel sign for diagnosing Crohn's disease ranged from 70% to 100% and 87% to 100%, respectively. There were significant differences in peristalsis between abnormal small bowel segments and the overall small bowel for Crohn's patients, but not in the overall small bowel between normal-MRE patients and Crohn's disease patients. Conclusion: Abnormal Crohn's small bowel segments have significantly decreased peristalsis compared to normal small bowel, which can be identified using cine BSSFP sequences as the frozen bowel sign. Springer Science+Business Media New York, 2014 MR enterography nationallicence Small bowel nationallicence Peristalsis nationallicence Motility nationallicence Cine MRI nationallicence Crohn's disease nationallicence Guglielmo Flavius Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut Mitchell Donald Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut O'Kane Patrick Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut Deshmukh Sandeep Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut Roth Christopher Department of Radiology, Methodist Hospital, Thomas Jefferson University, 2301 South Broad Street, 19148, Philadelphia, PA, USA aut Burach Ilene Shore Medical Center, 100 Medical Center Way, 08244, Somers Point, NJ, USA aut Burns Aaron Our Lady of Lourdes Medical Center, 1600 Haddon Avenue, 08103, Camden, NJ, USA aut Dulka Susan Radiology Center, M.C. 34-46, 1000 E Mountain Blvd., 18711, Wilkes-Barre, PA, USA aut Parker Laurence Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1150-1156 0942-8925 40:5<1150 2015 40 261 https://doi.org/10.1007/s00261-014-0258-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0258-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Guglielmo Flavius Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Mitchell Donald Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- O'Kane Patrick Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Deshmukh Sandeep Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Roth Christopher Department of Radiology, Methodist Hospital, Thomas Jefferson University, 2301 South Broad Street, 19148, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Burach Ilene Shore Medical Center, 100 Medical Center Way, 08244, Somers Point, NJ, USA aut NATIONALLICENCE 700 1- Burns Aaron Our Lady of Lourdes Medical Center, 1600 Haddon Avenue, 08103, Camden, NJ, USA aut NATIONALLICENCE 700 1- Dulka Susan Radiology Center, M.C. 34-46, 1000 E Mountain Blvd., 18711, Wilkes-Barre, PA, USA aut NATIONALLICENCE 700 1- Parker Laurence Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 19107, Philadelphia, PA, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1150-1156 0942-8925 40:5<1150 2015 40 261