Duodenal neuroendocrine tumors: retrospective evaluation of CT imaging features and pattern of metastatic disease on dual-phase MDCT with pathologic correlation

Verfasser / Beitragende:
[Salina Tsai, Satomi Kawamoto, Christopher Wolfgang, Ralph Hruban, Elliot Fishman]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/5(2015-06-01), 1121-1130
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0322-7  |2 doi 
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245 0 0 |a Duodenal neuroendocrine tumors: retrospective evaluation of CT imaging features and pattern of metastatic disease on dual-phase MDCT with pathologic correlation  |h [Elektronische Daten]  |c [Salina Tsai, Satomi Kawamoto, Christopher Wolfgang, Ralph Hruban, Elliot Fishman] 
520 3 |a Purpose: The purpose of the study is to evaluate the CT appearance and pattern of metastatic disease of patients with surgically resected well-differentiated duodenal neuroendocrine tumors who underwent pre-operative dual-phase CT. Methods: Clinical and pathologic records and CT images of 28 patients (average age 58.0years) following Whipple procedure were retrospectively reviewed. The size, morphology (polypoid, intraluminal mass or wall thickening, intramural mass), location, CT attenuation in the arterial and venous phases, and the presence of lymph node or liver metastases were recorded. Results: On CT, 19 patients (67.8%) had neuroendocrine tumors manifested as polypoid or intraluminal masses (38 lesions, multiple tumors in 3 patients), 4 patients (14.3%) had tumors manifested as wall thickening or intramural masses, and in 5 patients (17.9%), the primary tumor was not visualized. Lesions not seen at CT were less than 0.8cm on pathologic diagnosis. The mean size of polypoid tumors on CT was 1.2cm (range 0.3-3.8cm); 24 tumors were 1.0cm or smaller, and 14 tumors were larger than 1.0cm. Most lesions were hypervascular in the arterial phase (19/23 patients) with an increase in tumor enhancement in the venous phase in 14 patients (60.9%), decrease in enhancement in 7 patients (30.4%), and no change in enhancement in 2 patients (8.7%). Thirteen patients (46.4%) had metastatic disease from carcinoid tumor, most commonly regional enhancing lymphadenopathy. Conclusion: Duodenal carcinoid tumors commonly appear as an enhancing mass in either the arterial or venous phases. If a primary tumor is not seen in the duodenum, adjacent enhancing lymphadenopathy can be a clue to the presence of a duodenal carcinoid tumor. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Duodenum  |2 nationallicence 
690 7 |a Computed tomography  |2 nationallicence 
690 7 |a Carcinoid  |2 nationallicence 
690 7 |a Neuroendocrine tumor  |2 nationallicence 
700 1 |a Tsai  |D Salina  |u The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA  |4 aut 
700 1 |a Kawamoto  |D Satomi  |u The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA  |4 aut 
700 1 |a Wolfgang  |D Christopher  |u Department of Surgery, Johns Hopkins Hospital, 21231, Baltimore, MD, USA  |4 aut 
700 1 |a Hruban  |D Ralph  |u Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21231, Baltimore, MD, USA  |4 aut 
700 1 |a Fishman  |D Elliot  |u The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/5(2015-06-01), 1121-1130  |x 0942-8925  |q 40:5<1121  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0322-7  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0322-7  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tsai  |D Salina  |u The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kawamoto  |D Satomi  |u The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wolfgang  |D Christopher  |u Department of Surgery, Johns Hopkins Hospital, 21231, Baltimore, MD, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hruban  |D Ralph  |u Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21231, Baltimore, MD, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fishman  |D Elliot  |u The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/5(2015-06-01), 1121-1130  |x 0942-8925  |q 40:5<1121  |1 2015  |2 40  |o 261