caa a22 4500 605495122 CHVBK 20210128100529.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00261-014-0322-7 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0322-7 Duodenal neuroendocrine tumors: retrospective evaluation of CT imaging features and pattern of metastatic disease on dual-phase MDCT with pathologic correlation [Elektronische Daten] [Salina Tsai, Satomi Kawamoto, Christopher Wolfgang, Ralph Hruban, Elliot Fishman] Purpose: The purpose of the study is to evaluate the CT appearance and pattern of metastatic disease of patients with surgically resected well-differentiated duodenal neuroendocrine tumors who underwent pre-operative dual-phase CT. Methods: Clinical and pathologic records and CT images of 28 patients (average age 58.0years) following Whipple procedure were retrospectively reviewed. The size, morphology (polypoid, intraluminal mass or wall thickening, intramural mass), location, CT attenuation in the arterial and venous phases, and the presence of lymph node or liver metastases were recorded. Results: On CT, 19 patients (67.8%) had neuroendocrine tumors manifested as polypoid or intraluminal masses (38 lesions, multiple tumors in 3 patients), 4 patients (14.3%) had tumors manifested as wall thickening or intramural masses, and in 5 patients (17.9%), the primary tumor was not visualized. Lesions not seen at CT were less than 0.8cm on pathologic diagnosis. The mean size of polypoid tumors on CT was 1.2cm (range 0.3-3.8cm); 24 tumors were 1.0cm or smaller, and 14 tumors were larger than 1.0cm. Most lesions were hypervascular in the arterial phase (19/23 patients) with an increase in tumor enhancement in the venous phase in 14 patients (60.9%), decrease in enhancement in 7 patients (30.4%), and no change in enhancement in 2 patients (8.7%). Thirteen patients (46.4%) had metastatic disease from carcinoid tumor, most commonly regional enhancing lymphadenopathy. Conclusion: Duodenal carcinoid tumors commonly appear as an enhancing mass in either the arterial or venous phases. If a primary tumor is not seen in the duodenum, adjacent enhancing lymphadenopathy can be a clue to the presence of a duodenal carcinoid tumor. Springer Science+Business Media New York, 2014 Duodenum nationallicence Computed tomography nationallicence Carcinoid nationallicence Neuroendocrine tumor nationallicence Tsai Salina The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA aut Kawamoto Satomi The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA aut Wolfgang Christopher Department of Surgery, Johns Hopkins Hospital, 21231, Baltimore, MD, USA aut Hruban Ralph Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21231, Baltimore, MD, USA aut Fishman Elliot The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1121-1130 0942-8925 40:5<1121 2015 40 261 https://doi.org/10.1007/s00261-014-0322-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0322-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tsai Salina The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Kawamoto Satomi The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Wolfgang Christopher Department of Surgery, Johns Hopkins Hospital, 21231, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Hruban Ralph Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21231, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Fishman Elliot The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 21231, Baltimore, MD, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1121-1130 0942-8925 40:5<1121 2015 40 261