caa a22 4500 605495319 CHVBK 20210128100530.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00261-014-0271-1 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0271-1 Reducing the radiation dose for computed tomography colonography using model-based iterative reconstruction [Elektronische Daten] [Patrick Millerd, Robert Paden, Jeffrey Lund, Amy Hara, Wendy Stiles, Miao He, Qing Wu, C. Daniel Johnson] Purpose: To determine whether radiation doses during computed tomography (CT) colonography (CTC) can be further reduced while maintaining image quality using model-based iterative reconstruction (MBIR). Methods: Twenty patients underwent CTC at a standard dose in supine and prone positions and at a reduced dose in the supine position. All other scan parameters (except noise index) were held constant. Acquisitions were reconstructed using 3 algorithms: filtered back projection (FBP), adaptive statistical iterative reconstruction (ASIR), and MBIR. Noise was assessed quantitatively by comparing the SD in Hounsfield units at 5 standard locations. Qualitative assessment was made by 2 experienced radiologists blinded to technique who subjectively scored image quality, noise, and sharpness (from 0 to 4). Results: The standard-dose and reduced-dose CT dose index/dose-length product were 6.7/328 and 2.7mGy/129mGy-cm, respectively (60% reduction). Measured mean noise level increased from the standard to the reduced dose (FBP, from 58.6 to 97.2; ASIR from 35.8 to 60.6; and MBIR from 16.6 to 21.9). MBIR had significantly less noise than ASIR on 2-dimensional images at both standard and reduced doses (P<.01). Conclusions: Radiation dose in CTC using MBIR can be reduced by 60% while maintaining image quality and reducing image noise. Springer Science+Business Media New York, 2014 Adaptive statistical iterative reconstruction nationallicence Computed tomography nationallicence CT colonography nationallicence Iterative reconstruction nationallicence Model-based iterative reconstruction nationallicence Reduced dose nationallicence ASIR : Adaptive statistical iterative reconstruction nationallicence BMI : Body mass index (weight in kg divided by height in m2 [kg/m2]) nationallicence CT : Computed tomography nationallicence CTC : Computed tomography colonography nationallicence DLP : Dose-length product nationallicence FBP : Filtered back projection nationallicence HIPAA : Health Insurance Portability and Accountability Act nationallicence kVp : Kilovolts peak nationallicence mAs : Milliamperes-second nationallicence MBIR : Model-based iterative reconstruction nationallicence MDCT : Multidetector computed tomography nationallicence mSv : Millisievert nationallicence Millerd Patrick Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut Paden Robert Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut Lund Jeffrey Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut Hara Amy Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut Stiles Wendy Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut He Miao Arizona State University, Tempe, AZ, USA aut Wu Qing Division of Health Sciences Research, Mayo Clinic, Scottsdale, AZ, USA aut Daniel Johnson C. Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1183-1189 0942-8925 40:5<1183 2015 40 261 https://doi.org/10.1007/s00261-014-0271-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0271-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Millerd Patrick Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut NATIONALLICENCE 700 1- Paden Robert Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut NATIONALLICENCE 700 1- Lund Jeffrey Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut NATIONALLICENCE 700 1- Hara Amy Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut NATIONALLICENCE 700 1- Stiles Wendy Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut NATIONALLICENCE 700 1- He Miao Arizona State University, Tempe, AZ, USA aut NATIONALLICENCE 700 1- Wu Qing Division of Health Sciences Research, Mayo Clinic, Scottsdale, AZ, USA aut NATIONALLICENCE 700 1- Daniel Johnson C. Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, 85259, Scottsdale, AZ, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/5(2015-06-01), 1183-1189 0942-8925 40:5<1183 2015 40 261