Low yield of chemical shift MRI for characterization of adrenal lesions with high attenuation density on unenhanced CT

Verfasser / Beitragende:
[Ronnie Sebro, Rizwan Aslam, Valdair Muglia, Z. Wang, Antonio Westphalen]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/2(2015-02-01), 318-326
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0208-8  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0208-8 
245 0 0 |a Low yield of chemical shift MRI for characterization of adrenal lesions with high attenuation density on unenhanced CT  |h [Elektronische Daten]  |c [Ronnie Sebro, Rizwan Aslam, Valdair Muglia, Z. Wang, Antonio Westphalen] 
520 3 |a Purpose: To investigate the threshold unenhanced CT density of adrenal nodules at which further evaluation with chemical shift MRI is unlikely to be definitive and therefore not helpful in further characterizing some indeterminate adrenal lesions. Methods: Retrospective evaluation of 44 adrenal lesions imaged with unenhanced CT and chemical shift MRI and followed for at least 1year. Qualitative and quantitative assessment of signal loss on chemical shift MRI was performed. Adenomas were diagnosed if the lesion measured equal or less than 10HU on unenhanced CT; on MRI a SI index greater than 16.5% or adrenal:spleen chemical shift ratio less than 0.71 was considered diagnostic of adenoma. Results: 31.8% (14/44), 47.7% (21/44), and 20.5% (9/44) of the adrenal lesions had an unenhanced CT attenuation density ≤10, 10-30, and >30HU. Adrenal lesions with an unenhanced CT density 10-30 and >30HU had a 76.2% (16/21) and a 33.3% (3/9) chance of being categorized as an adenoma using MRI SI index, respectively. Conclusions: Adrenal lesions with unenhanced attenuation CT density >30HU had a 66.6% of remaining indeterminate even after evaluation with chemical shift MRI. Advances in knowledge: Chemical shift MRI is reasonable for evaluating adrenal lesions with an unenhanced CT attenuation density less than 30HU. The likelihood of chemical shift MRI detecting signal loss in lesions CT density greater than 30HU, however, is low. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Adrenal adenoma  |2 nationallicence 
690 7 |a Adrenal lesion  |2 nationallicence 
690 7 |a Adrenal nodule  |2 nationallicence 
690 7 |a Adrenal mass  |2 nationallicence 
690 7 |a Chemical shift  |2 nationallicence 
690 7 |a Magnetic resonance imaging (MRI)  |2 nationallicence 
690 7 |a Computed tomography (CT)  |2 nationallicence 
700 1 |a Sebro  |D Ronnie  |u Massachusetts General Hospital Imaging, 55 Fruit Street, 02114, Boston, MA, USA  |4 aut 
700 1 |a Aslam  |D Rizwan  |u Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA  |4 aut 
700 1 |a Muglia  |D Valdair  |u Ribeirao Preto School of Medicine, University of São Paulo (USP), Av. Bandeirantes 3900, 6° andar, 14048-900, Ribeirão Preto, SP, Brazil  |4 aut 
700 1 |a Wang  |D Z.  |u Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA  |4 aut 
700 1 |a Westphalen  |D Antonio  |u Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/2(2015-02-01), 318-326  |x 0942-8925  |q 40:2<318  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0208-8  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0208-8  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sebro  |D Ronnie  |u Massachusetts General Hospital Imaging, 55 Fruit Street, 02114, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Aslam  |D Rizwan  |u Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Muglia  |D Valdair  |u Ribeirao Preto School of Medicine, University of São Paulo (USP), Av. Bandeirantes 3900, 6° andar, 14048-900, Ribeirão Preto, SP, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wang  |D Z.  |u Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Westphalen  |D Antonio  |u Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/2(2015-02-01), 318-326  |x 0942-8925  |q 40:2<318  |1 2015  |2 40  |o 261