caa a22 4500 60549536X CHVBK 20210128100531.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00261-014-0208-8 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0208-8 Low yield of chemical shift MRI for characterization of adrenal lesions with high attenuation density on unenhanced CT [Elektronische Daten] [Ronnie Sebro, Rizwan Aslam, Valdair Muglia, Z. Wang, Antonio Westphalen] Purpose: To investigate the threshold unenhanced CT density of adrenal nodules at which further evaluation with chemical shift MRI is unlikely to be definitive and therefore not helpful in further characterizing some indeterminate adrenal lesions. Methods: Retrospective evaluation of 44 adrenal lesions imaged with unenhanced CT and chemical shift MRI and followed for at least 1year. Qualitative and quantitative assessment of signal loss on chemical shift MRI was performed. Adenomas were diagnosed if the lesion measured equal or less than 10HU on unenhanced CT; on MRI a SI index greater than 16.5% or adrenal:spleen chemical shift ratio less than 0.71 was considered diagnostic of adenoma. Results: 31.8% (14/44), 47.7% (21/44), and 20.5% (9/44) of the adrenal lesions had an unenhanced CT attenuation density ≤10, 10-30, and >30HU. Adrenal lesions with an unenhanced CT density 10-30 and >30HU had a 76.2% (16/21) and a 33.3% (3/9) chance of being categorized as an adenoma using MRI SI index, respectively. Conclusions: Adrenal lesions with unenhanced attenuation CT density >30HU had a 66.6% of remaining indeterminate even after evaluation with chemical shift MRI. Advances in knowledge: Chemical shift MRI is reasonable for evaluating adrenal lesions with an unenhanced CT attenuation density less than 30HU. The likelihood of chemical shift MRI detecting signal loss in lesions CT density greater than 30HU, however, is low. Springer Science+Business Media New York, 2014 Adrenal adenoma nationallicence Adrenal lesion nationallicence Adrenal nodule nationallicence Adrenal mass nationallicence Chemical shift nationallicence Magnetic resonance imaging (MRI) nationallicence Computed tomography (CT) nationallicence Sebro Ronnie Massachusetts General Hospital Imaging, 55 Fruit Street, 02114, Boston, MA, USA aut Aslam Rizwan Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA aut Muglia Valdair Ribeirao Preto School of Medicine, University of São Paulo (USP), Av. Bandeirantes 3900, 6° andar, 14048-900, Ribeirão Preto, SP, Brazil aut Wang Z. Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA aut Westphalen Antonio Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/2(2015-02-01), 318-326 0942-8925 40:2<318 2015 40 261 https://doi.org/10.1007/s00261-014-0208-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0208-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sebro Ronnie Massachusetts General Hospital Imaging, 55 Fruit Street, 02114, Boston, MA, USA aut NATIONALLICENCE 700 1- Aslam Rizwan Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Muglia Valdair Ribeirao Preto School of Medicine, University of São Paulo (USP), Av. Bandeirantes 3900, 6° andar, 14048-900, Ribeirão Preto, SP, Brazil aut NATIONALLICENCE 700 1- Wang Z. Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Westphalen Antonio Departments of Radiology and Biomedical Imaging and Urology, University of California, San Francisco, 505 Parnassus Avenue, 94143, San Francisco, CA, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/2(2015-02-01), 318-326 0942-8925 40:2<318 2015 40 261