Navigated three-dimensional T1-weighted gradient-echo sequence for gadoxetic acid liver magnetic resonance imaging in patients with limited breath-holding capacity

Verfasser / Beitragende:
[Jeong Yoon, Jeong Lee, Eun Lee, Jeehyun Baek, Sangwoo Lee, Yuji Iwadate, Joon Han, Byung Choi]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/2(2015-02-01), 278-288
Format:
Artikel (online)
ID: 605495424
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024 7 0 |a 10.1007/s00261-014-0214-x  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0214-x 
245 0 0 |a Navigated three-dimensional T1-weighted gradient-echo sequence for gadoxetic acid liver magnetic resonance imaging in patients with limited breath-holding capacity  |h [Elektronische Daten]  |c [Jeong Yoon, Jeong Lee, Eun Lee, Jeehyun Baek, Sangwoo Lee, Yuji Iwadate, Joon Han, Byung Choi] 
520 3 |a Purpose: To determine whether a navigator-gated three-dimensional T1-weighted gradient-echo sequence (T1W-GRE, navigated LAVA) can improve diagnostic performance for the detection of focal liver lesions (FLLs) compared to standard breath-hold (BH) T1W-GRE breath-hold LAVA (BH-LAVA) during the hepatobiliary phase (HBP) of gadoxetic acid liver magnetic resonance imaging (MRI) in patients with limited breath-holding capacity. Materials and methods: This retrospective study was approved by our institutional review board and the requirement for informed consent was waived. We included 372 patients who underwent liver MRI including both navigated LAVA and BH-LAVA sequences. Overall image quality of the two HBP image sets was compared. In patients with limited breath-holding capacity, diagnostic performances in detecting FLLs on the two HBP images were compared using jackknife-alternative free-response receiver-operating characteristic (JAFROC) analysis by two reviewers. Results: There were 13 cases (13/372; 3.5%) of image acquisition failure using the navigated LAVA sequence due to severe irregular breathing, and 50 of 359 patients had limited breath-holding capacity. In these patients, overall image quality of navigated LAVA (2.78±0.95) was significantly better than that of BH-LAVA (2.42±0.81, P<0.005), and both readers showed significantly higher JAFROC figure-of-merit values with navigated LAVA compared to BH-LAVA (0.94 and 0.86 in reviewer 1, respectively; 0.89 and 0.83 in reviewer 2, respectively, P<0.005). Overall image quality of navigated LAVA was also better than that of BH-LAVA in patients with sufficient breath-holding capacity (n=309, 3.96±0.88, 3.81±0.66, respectively, P<0.001). Conclusion: The navigated LAVA sequence could provide better image quality and diagnostic performance in detecting FLLs than BH-LAVA in patients with limited breath-holding capacity during HBP of gadoxetic acid MRI. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Magnetic resonance imaging  |2 nationallicence 
690 7 |a Hepatobiliary phase  |2 nationallicence 
690 7 |a Respiratory-gated imaging  |2 nationallicence 
690 7 |a Gd-EOB-DTPA  |2 nationallicence 
690 7 |a Gadoxetic acid  |2 nationallicence 
700 1 |a Yoon  |D Jeong  |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Lee  |D Jeong  |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Lee  |D Eun  |u Department of Radiology, National Cancer Center, Goyang-si, Gyeonggi-do, Korea  |4 aut 
700 1 |a Baek  |D Jeehyun  |u Human Medical Imaging & Intervention Center, Seoul, Korea  |4 aut 
700 1 |a Lee  |D Sangwoo  |u Global Applied Science Laboratory, GE Healthcare, Seoul, Korea  |4 aut 
700 1 |a Iwadate  |D Yuji  |u Global Applied Science Laboratory, GE Healthcare, Hino, Tokyo, Japan  |4 aut 
700 1 |a Han  |D Joon  |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Choi  |D Byung  |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/2(2015-02-01), 278-288  |x 0942-8925  |q 40:2<278  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0214-x  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0214-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yoon  |D Jeong  |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lee  |D Jeong  |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lee  |D Eun  |u Department of Radiology, National Cancer Center, Goyang-si, Gyeonggi-do, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Baek  |D Jeehyun  |u Human Medical Imaging & Intervention Center, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lee  |D Sangwoo  |u Global Applied Science Laboratory, GE Healthcare, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Iwadate  |D Yuji  |u Global Applied Science Laboratory, GE Healthcare, Hino, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Han  |D Joon  |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Choi  |D Byung  |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/2(2015-02-01), 278-288  |x 0942-8925  |q 40:2<278  |1 2015  |2 40  |o 261