caa a22 4500 605495459 CHVBK 20210128100531.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00261-014-0202-1 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0202-1 CT sensitivities for large (≥3cm) adrenal adenoma and cortical carcinoma [Elektronische Daten] [Sung Park, Byung Park, Jung Park, Chan Kim] Purpose: To retrospectively compare computed tomography (CT) sensitivities of large (≥3cm) adenoma and cortical carcinoma. Methods: Between January 2004 and November 2012, 43 non-oncologic patients with 43 adrenal masses [31 large adenomas, and 12 carcinomas] underwent unenhanced CT, early contrast-enhanced CT, and delayed contrast-enhanced CT scans prior to adrenalectomy. Three types of region-of-interest (ROI) were used on early contrast-enhanced CT images:aROI (large ROI) covering more than half of a mass and two small ROIs fitted to the highest (high ROI) or lowest (low ROI) attenuation area. These ROIs were also placed in the same area on the other CT images. Adenoma was diagnosed if a mass measured≤10 HU on unenhanced CT image, or if it had≥60% absolute percentage washout (APW)or≥40% relative percentage washout (RPW).Carcinoma was diagnosed if a mass had<60% APW and<40% RPW. CT sensitivities for large adenoma and carcinoma were compared. Results: CT sensitivities for large adenoma vs. carcinoma were 64.5% (20/31) vs. 100% (12/12) using a large ROI, 100% (31/31) vs. 50.0% (6/12) using a high ROI, and 51.6% (16/31) vs. 100% (12/12) using a low ROIs, respectively. Conclusions: CT sensitivities for large adenoma and cortical carcinoma are influenced by the size or location of an ROI.A large ROI helps to minimize loss of CT sensitivity for large adenoma and to detect carcinoma. Springer Science+Business Media New York, 2014 Adrenal gland nationallicence Adenoma nationallicence Carcinoma nationallicence Computed tomography nationallicence Park Sung Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut Park Byung Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut Park Jung Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut Kim Chan Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/2(2015-02-01), 310-317 0942-8925 40:2<310 2015 40 261 https://doi.org/10.1007/s00261-014-0202-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0202-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Park Sung Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut NATIONALLICENCE 700 1- Park Byung Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut NATIONALLICENCE 700 1- Park Jung Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Chan Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/2(2015-02-01), 310-317 0942-8925 40:2<310 2015 40 261