99mTc-phytate trans-splenic portal scintigraphy in the diagnosis of cirrhotic portal hypertension and compensatory circulation

Verfasser / Beitragende:
[Aakif Khan, Javaid Irfanullah, Syed Shah, Shazia Fatima]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/2(2015-02-01), 258-264
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0204-z  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0204-z 
245 0 0 |a 99mTc-phytate trans-splenic portal scintigraphy in the diagnosis of cirrhotic portal hypertension and compensatory circulation  |h [Elektronische Daten]  |c [Aakif Khan, Javaid Irfanullah, Syed Shah, Shazia Fatima] 
520 3 |a Background and aim: The trans-splenic portal scintigraphy (TPS) was evaluated as a diagnostic tool in the post viral hepatitis cirrhotic patients of various classes of Child Pugh's (CP) classification. The main aim was to determine the portosystemic shunt index (PSSI) and to compare the results with various clinical grades of disease severity in liver cirrhosis. Methods: TPS was performed on 72 patients and 10 controls and PSSI was derived. All the 72 patients were categorized according to CP classification into three classes. The cirrhotic patients were categorized as CP A (n=24),CP B (n=22), and CP C (n=26)according to CP criteria. PSSI was compared with different CP classes. Results: In the controlled population, the splenic vein was normal in shape and the mean PSSI was calculated to be 0.178±0.031 (n=10). For CP classes A, B, and C, the mean PSSI was 0.36±0.04, 0.45±0.05, and 0.54±0.04 (n=26), respectively. There was statistical significance among groups (p≤0.01).The collateral vessels were mostly uphill or complex. The PSSI index increased as the CP score worsened from A to C. Conclusion: PSSI is a useful and minimally invasive tool to detect and quantify the shunt severity, which correlates well with different clinical grades of disease severity. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Cirrhosis  |2 nationallicence 
690 7 |a Portal hypertension  |2 nationallicence 
690 7 |a Portosystemic shunt  |2 nationallicence 
690 7 |a Portal scintigraphy  |2 nationallicence 
700 1 |a Khan  |D Aakif  |u Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan  |4 aut 
700 1 |a Irfanullah  |D Javaid  |u Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan  |4 aut 
700 1 |a Shah  |D Syed  |u Chemistry Department, University of Peshawar, Peshawar, Pakistan  |4 aut 
700 1 |a Fatima  |D Shazia  |u Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/2(2015-02-01), 258-264  |x 0942-8925  |q 40:2<258  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0204-z  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0204-z  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Khan  |D Aakif  |u Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Irfanullah  |D Javaid  |u Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shah  |D Syed  |u Chemistry Department, University of Peshawar, Peshawar, Pakistan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fatima  |D Shazia  |u Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/2(2015-02-01), 258-264  |x 0942-8925  |q 40:2<258  |1 2015  |2 40  |o 261