caa a22 4500 605495505 CHVBK 20210128100531.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00261-014-0204-z doi (NATIONALLICENCE)springer-10.1007/s00261-014-0204-z 99mTc-phytate trans-splenic portal scintigraphy in the diagnosis of cirrhotic portal hypertension and compensatory circulation [Elektronische Daten] [Aakif Khan, Javaid Irfanullah, Syed Shah, Shazia Fatima] Background and aim: The trans-splenic portal scintigraphy (TPS) was evaluated as a diagnostic tool in the post viral hepatitis cirrhotic patients of various classes of Child Pugh's (CP) classification. The main aim was to determine the portosystemic shunt index (PSSI) and to compare the results with various clinical grades of disease severity in liver cirrhosis. Methods: TPS was performed on 72 patients and 10 controls and PSSI was derived. All the 72 patients were categorized according to CP classification into three classes. The cirrhotic patients were categorized as CP A (n=24),CP B (n=22), and CP C (n=26)according to CP criteria. PSSI was compared with different CP classes. Results: In the controlled population, the splenic vein was normal in shape and the mean PSSI was calculated to be 0.178±0.031 (n=10). For CP classes A, B, and C, the mean PSSI was 0.36±0.04, 0.45±0.05, and 0.54±0.04 (n=26), respectively. There was statistical significance among groups (p≤0.01).The collateral vessels were mostly uphill or complex. The PSSI index increased as the CP score worsened from A to C. Conclusion: PSSI is a useful and minimally invasive tool to detect and quantify the shunt severity, which correlates well with different clinical grades of disease severity. Springer Science+Business Media New York, 2014 Cirrhosis nationallicence Portal hypertension nationallicence Portosystemic shunt nationallicence Portal scintigraphy nationallicence Khan Aakif Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan aut Irfanullah Javaid Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan aut Shah Syed Chemistry Department, University of Peshawar, Peshawar, Pakistan aut Fatima Shazia Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/2(2015-02-01), 258-264 0942-8925 40:2<258 2015 40 261 https://doi.org/10.1007/s00261-014-0204-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0204-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Khan Aakif Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan aut NATIONALLICENCE 700 1- Irfanullah Javaid Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan aut NATIONALLICENCE 700 1- Shah Syed Chemistry Department, University of Peshawar, Peshawar, Pakistan aut NATIONALLICENCE 700 1- Fatima Shazia Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/2(2015-02-01), 258-264 0942-8925 40:2<258 2015 40 261