Diffusion-weighted magnetic resonance imaging indicates the severity of acute pancreatitis

Verfasser / Beitragende:
[Franklin de Freitas Tertulino, Vladimir Schraibman, José Ardengh, Danilo do Espírito-Santo, Sergio Ajzen, Franz Torrez, Edson Lobo, Jacob Szejnfeld, Suzan Goldman]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/2(2015-02-01), 265-271
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0205-y  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0205-y 
245 0 0 |a Diffusion-weighted magnetic resonance imaging indicates the severity of acute pancreatitis  |h [Elektronische Daten]  |c [Franklin de Freitas Tertulino, Vladimir Schraibman, José Ardengh, Danilo do Espírito-Santo, Sergio Ajzen, Franz Torrez, Edson Lobo, Jacob Szejnfeld, Suzan Goldman] 
520 3 |a Purpose: To test the use of diffusion-weighted magnetic resonance imaging (DW-MRI) to differentiate between different degrees of severity of acute pancreatitis (AP). Method: Thirty-six patients who underwent DW-MRI and magnetic resonance cholangiopancreatography were divided into patients with mild AP (mAP, n=15), patients with necrotizing AP (nAP, n=8), and patients with a normal pancreas (nP, n=15; controls). The pancreas was divided into head, body, and tail, and each segment was classified according to image features: pattern 1, normal; pattern 2, mild inflammation; and pattern 3, necrosis. Apparent diffusion coefficients (ADCs) were measured in each segment and correlated with clinical diagnoses. Results: A total of 108 segments was assessed (three segments per patient). Segments classified as pattern 1 in the nP and mAP groups showed similar ADC values (P=0.29). ADC values calculated for the pancreatic segments grouped according to the different image patterns (1-3) were significantly different (P<0.001). Comparisons revealed significant differences in signal intensity between all three patterns (P<0.05). Conclusions: DW-MRI was a compatible and safe image option to differentiate tissue image patterns in patients with mAP, nAP, and nP, mainly in those with contraindications to contrast-enhanced MRI (which is classically required for determining the presence of necrosis) or computed tomography. ADC measures allowed precise differentiation between patterns 1, 2, and 3. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Acute necrotizing pancreatitis  |2 nationallicence 
690 7 |a Diffusion magnetic resonance imaging  |2 nationallicence 
690 7 |a Differential diagnosis  |2 nationallicence 
700 1 |a de Freitas Tertulino  |D Franklin  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
700 1 |a Schraibman  |D Vladimir  |u Department of Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
700 1 |a Ardengh  |D José  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
700 1 |a do Espírito-Santo  |D Danilo  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
700 1 |a Ajzen  |D Sergio  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
700 1 |a Torrez  |D Franz  |u Department of Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
700 1 |a Lobo  |D Edson  |u Department of Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
700 1 |a Szejnfeld  |D Jacob  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
700 1 |a Goldman  |D Suzan  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/2(2015-02-01), 265-271  |x 0942-8925  |q 40:2<265  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0205-y  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0205-y  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a de Freitas Tertulino  |D Franklin  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Schraibman  |D Vladimir  |u Department of Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ardengh  |D José  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a do Espírito-Santo  |D Danilo  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ajzen  |D Sergio  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Torrez  |D Franz  |u Department of Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lobo  |D Edson  |u Department of Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Szejnfeld  |D Jacob  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Goldman  |D Suzan  |u Department of Diagnostic Imaging, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/2(2015-02-01), 265-271  |x 0942-8925  |q 40:2<265  |1 2015  |2 40  |o 261