Mathematical Analysis of the Effects of HIV-Malaria Co-infection on Workplace Productivity

Verfasser / Beitragende:
[Baba Seidu, Oluwole Makinde, Ibrahim Seini]
Ort, Verlag, Jahr:
2015
Enthalten in:
Acta Biotheoretica, 63/2(2015-06-01), 151-182
Format:
Artikel (online)
ID: 60549746X
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024 7 0 |a 10.1007/s10441-015-9255-y  |2 doi 
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245 0 0 |a Mathematical Analysis of the Effects of HIV-Malaria Co-infection on Workplace Productivity  |h [Elektronische Daten]  |c [Baba Seidu, Oluwole Makinde, Ibrahim Seini] 
520 3 |a In this paper, a nonlinear dynamical system is proposed and qualitatively analyzed to study the dynamics and effects of HIV-malaria co-infection in the workplace. Basic reproduction numbers of sub-models are derived and are shown to have LAS disease-free equilibria when their respective basic reproduction numbers are less than unity. Conditions for existence of endemic equilibria of sub-models are also derived. Unlike the HIV-only model, the malaria-only model is shown to exhibit a backward bifurcation under certain conditions. Conditions for optimal control of the co-infection are derived using the Pontryagin's maximum principle. Numerical experimentation on the resulting optimality system is performed. Using the incremental cost-effectiveness ratio, it is observed that combining preventative measures for both diseases is the best strategy for optimal control of HIV-malaria co-infection at the workplace. 
540 |a Springer Science+Business Media Dordrecht, 2015 
690 7 |a HIV  |2 nationallicence 
690 7 |a Malaria  |2 nationallicence 
690 7 |a Optimal control  |2 nationallicence 
690 7 |a Productivity  |2 nationallicence 
700 1 |a Seidu  |D Baba  |u Applied Mathematics Department, Faculty of Mathematical Sciences, University for Development, Navrongo, Ghana  |4 aut 
700 1 |a Makinde  |D Oluwole  |u Faculty of Military Science, Stellenbosch University, Private Bag X2, 7395, Saldanha, South Africa  |4 aut 
700 1 |a Seini  |D Ibrahim  |u Applied Mathematics Department, Faculty of Mathematical Sciences, University for Development, Navrongo, Ghana  |4 aut 
773 0 |t Acta Biotheoretica  |d Springer Netherlands  |g 63/2(2015-06-01), 151-182  |x 0001-5342  |q 63:2<151  |1 2015  |2 63  |o 10441 
856 4 0 |u https://doi.org/10.1007/s10441-015-9255-y  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Seidu  |D Baba  |u Applied Mathematics Department, Faculty of Mathematical Sciences, University for Development, Navrongo, Ghana  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Makinde  |D Oluwole  |u Faculty of Military Science, Stellenbosch University, Private Bag X2, 7395, Saldanha, South Africa  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Seini  |D Ibrahim  |u Applied Mathematics Department, Faculty of Mathematical Sciences, University for Development, Navrongo, Ghana  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Acta Biotheoretica  |d Springer Netherlands  |g 63/2(2015-06-01), 151-182  |x 0001-5342  |q 63:2<151  |1 2015  |2 63  |o 10441