caa a22 4500 605498261 CHVBK 20210128100545.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00253-015-6632-z doi (NATIONALLICENCE)springer-10.1007/s00253-015-6632-z Changes in intestinal bacterial communities are closely associated with shrimp disease severity [Elektronische Daten] [Jinbo Xiong, Kai Wang, Jinfeng Wu, Linglin Qiuqian, Kunjie Yang, Yunxia Qian, Demin Zhang] Increasing evidence has revealed a close association between intestinal bacterial communities and human health. However, given that host phylogeny shapes the composition of intestinal microbiota, it is unclear whether changes in intestinal microbiota structure in relation to shrimp health status. In this study, we collected shrimp and seawater samples from ponds with healthy and diseased shrimps to understand variations in bacterial communities among habitats (water and intestine) and/or health status. The bacterial communities were clustered according to the original habitat and health status. Habitat and health status constrained 14.6 and 7.7% of the variation in bacterial communities, respectively. Changes in shrimp intestinal bacterial communities occurred in parallel with changes in disease severity, reflecting the transition from a healthy to a diseased state. This pattern was further evidenced by 38 bacterial families that were significantly different in abundance between healthy and diseased shrimps; moderate changes were observed in shrimps with sub-optimal health. In addition, within a given bacterial family, the patterns of enrichment or decrease were consistent with the known functions of those bacteria. Furthermore, the identified 119 indicator taxa exhibited a discriminative pattern similar to the variation in the community as a whole. Overall, this study suggests that changes in intestinal bacterial communities are closely associated with the severity of shrimp disease and that indicator taxa can be used to evaluate shrimp health status. Springer-Verlag Berlin Heidelberg, 2015 Shrimp intestinal bacterial community nationallicence Disease severity nationallicence Indicator taxa nationallicence Discriminative pattern nationallicence Xiong Jinbo School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut Wang Kai School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut Wu Jinfeng School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut Qiuqian Linglin School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut Yang Kunjie School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut Qian Yunxia School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut Zhang Demin School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/16(2015-08-01), 6911-6919 0175-7598 99:16<6911 2015 99 253 https://doi.org/10.1007/s00253-015-6632-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00253-015-6632-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Xiong Jinbo School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut NATIONALLICENCE 700 1- Wang Kai School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut NATIONALLICENCE 700 1- Wu Jinfeng School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut NATIONALLICENCE 700 1- Qiuqian Linglin School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut NATIONALLICENCE 700 1- Yang Kunjie School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut NATIONALLICENCE 700 1- Qian Yunxia School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut NATIONALLICENCE 700 1- Zhang Demin School of Marine Sciences, Ningbo University, 315211, Ningbo, China aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/16(2015-08-01), 6911-6919 0175-7598 99:16<6911 2015 99 253