caa a22 4500 605498377 CHVBK 20210128100546.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00253-015-6788-6 doi (NATIONALLICENCE)springer-10.1007/s00253-015-6788-6 Isomerases for biotransformation of D-hexoses [Elektronische Daten] [Wanmeng Mu, Lina Yu, Wenli Zhang, Tao Zhang, Bo Jiang] Monosaccharides are polyhydroxyl compounds containing several chiral carbons, giving rise to tens of isomeric forms. Only minority of them are natural carbohydrates existing in nature abundantly, and most of them are rarely in nature, called rare sugars. These rare sugars attract increasing attention because of their low-calorie property and promising beneficial effects. Izumoring strategy has been established for linking all monosaccharides by three types of enzymes including ketose 3-epimerases, polyol dehydrogenases, and aldose isomerases. Recently, more attention has been paid on the Izumoring of hexoses, especially the D-zone hexoses. So far, at least ten isomerases have been used for the isomerization reactions between D-aldohexoses and D-ketohexoses. In this article, the interconnections and potential physiological effects of D-ketohexoses and D-aldohexoses are summarized, the D-zone hexose Izumoring is shown by giving the exact biocatalysts, and importantly, the isomerases for D-hexose biotransformation are reviewed in detail. Springer-Verlag Berlin Heidelberg, 2015 Aldose isomerase nationallicence Biotransformation nationallicence Hexose nationallicence Monosaccharide nationallicence Rare sugar nationallicence Mu Wanmeng State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut Yu Lina State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut Zhang Wenli State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut Zhang Tao State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut Jiang Bo State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/16(2015-08-01), 6571-6584 0175-7598 99:16<6571 2015 99 253 https://doi.org/10.1007/s00253-015-6788-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00253-015-6788-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mu Wanmeng State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut NATIONALLICENCE 700 1- Yu Lina State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut NATIONALLICENCE 700 1- Zhang Wenli State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut NATIONALLICENCE 700 1- Zhang Tao State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut NATIONALLICENCE 700 1- Jiang Bo State Key Laboratory of Food Science and Technology, Ministry of Education, Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/16(2015-08-01), 6571-6584 0175-7598 99:16<6571 2015 99 253