Enzymatic synthesis and modification of structured phospholipids: recent advances in enzyme preparation and biocatalytic processes

Verfasser / Beitragende:
[Shinji Hama, Chiaki Ogino, Akihiko Kondo]
Ort, Verlag, Jahr:
2015
Enthalten in:
Applied Microbiology and Biotechnology, 99/19(2015-10-01), 7879-7891
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00253-015-6845-1  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00253-015-6845-1 
245 0 0 |a Enzymatic synthesis and modification of structured phospholipids: recent advances in enzyme preparation and biocatalytic processes  |h [Elektronische Daten]  |c [Shinji Hama, Chiaki Ogino, Akihiko Kondo] 
520 3 |a Phospholipids (PLs) containing specific polar head groups and fatty acids, artificially synthesized from a complex mixture of natural PLs, have considerable industrial applications. The biocatalytic approaches to synthesizing structured PLs are of great interest because the enzymes used show high selectivity and performance under mild conditions, leading to the generation of products that cannot easily be obtained by chemical catalysis. Although the limited supply of phospholipases (e.g., phospholipase D) has thus far been an obstacle to the widespread use of enzymatic processing, recent advances in enzyme preparation have opened up various applications for PL modification. In this review, attempts to increase the productivity and utility of microbial phospholipases and lipases are presented. We also summarize recent developments in enzyme-catalyzed modification of PLs, focusing particularly on the relevant reactions, bioreactor design, and novel proof-of-concept experiments. 
540 |a Springer-Verlag Berlin Heidelberg, 2015 
690 7 |a Bioreactor  |2 nationallicence 
690 7 |a Enzyme production  |2 nationallicence 
690 7 |a Lecithin  |2 nationallicence 
690 7 |a Phospholipases  |2 nationallicence 
690 7 |a Phospholipid modification  |2 nationallicence 
700 1 |a Hama  |D Shinji  |u Research & Development Laboratory, Bio-energy Corporation, 2-9-7 Minaminanamatsu, 660-0053, Amagasaki, Japan  |4 aut 
700 1 |a Ogino  |D Chiaki  |u Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, 657-8501, Kobe, Japan  |4 aut 
700 1 |a Kondo  |D Akihiko  |u Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, 657-8501, Kobe, Japan  |4 aut 
773 0 |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/19(2015-10-01), 7879-7891  |x 0175-7598  |q 99:19<7879  |1 2015  |2 99  |o 253 
856 4 0 |u https://doi.org/10.1007/s00253-015-6845-1  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00253-015-6845-1  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hama  |D Shinji  |u Research & Development Laboratory, Bio-energy Corporation, 2-9-7 Minaminanamatsu, 660-0053, Amagasaki, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ogino  |D Chiaki  |u Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, 657-8501, Kobe, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kondo  |D Akihiko  |u Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, 657-8501, Kobe, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/19(2015-10-01), 7879-7891  |x 0175-7598  |q 99:19<7879  |1 2015  |2 99  |o 253