caa a22 4500 60549911X CHVBK 20210128100549.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00253-015-6426-3 doi (NATIONALLICENCE)springer-10.1007/s00253-015-6426-3 Applications of bacterial cellulose and its composites in biomedicine [Elektronische Daten] [J. Rajwade, K. Paknikar, J. Kumbhar] Bacterial cellulose produced by few but specific microbial genera is an extremely pure natural exopolysaccharide. Besides providing adhesive properties and a competitive advantage to the cellulose over-producer, bacterial cellulose confers UV protection, ensures maintenance of an aerobic environment, retains moisture, protects against heavy metal stress, etc. This unique nanostructured matrix is being widely explored for various medical and nonmedical applications. It can be produced in various shapes and forms because of which it finds varied uses in biomedicine. The attributes of bacterial cellulose such as biocompatibility, haemocompatibility, mechanical strength, microporosity and biodegradability with its unique surface chemistry make it ideally suited for a plethora of biomedical applications. This review highlights these qualities of bacterial cellulose in detail with emphasis on reports that prove its utility in biomedicine. It also gives an in-depth account of various biomedical applications ranging from implants and scaffolds for tissue engineering, carriers for drug delivery, wound-dressing materials, etc. that are reported until date. Besides, perspectives on limitations of commercialisation of bacterial cellulose have been presented. This review is also an update on the variety of low-cost substrates used for production of bacterial cellulose and its nonmedical applications and includes patents and commercial products based on bacterial cellulose. Springer-Verlag Berlin Heidelberg, 2015 Bacterial cellulose nationallicence Nanocomposites nationallicence Biomedical applications nationallicence Biomaterials nationallicence Rajwade J. Centre for Nanobioscience, Agharkar Research Institute, G. G. Agarkar Road, 411 004, Pune, India aut Paknikar K. Centre for Nanobioscience, Agharkar Research Institute, G. G. Agarkar Road, 411 004, Pune, India aut Kumbhar J. Centre for Nanobioscience, Agharkar Research Institute, G. G. Agarkar Road, 411 004, Pune, India aut Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/6(2015-03-01), 2491-2511 0175-7598 99:6<2491 2015 99 253 https://doi.org/10.1007/s00253-015-6426-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00253-015-6426-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rajwade J. Centre for Nanobioscience, Agharkar Research Institute, G. G. Agarkar Road, 411 004, Pune, India aut NATIONALLICENCE 700 1- Paknikar K. Centre for Nanobioscience, Agharkar Research Institute, G. G. Agarkar Road, 411 004, Pune, India aut NATIONALLICENCE 700 1- Kumbhar J. Centre for Nanobioscience, Agharkar Research Institute, G. G. Agarkar Road, 411 004, Pune, India aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/6(2015-03-01), 2491-2511 0175-7598 99:6<2491 2015 99 253