caa a22 4500 605499357 CHVBK 20210128100550.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00253-015-6903-8 doi (NATIONALLICENCE)springer-10.1007/s00253-015-6903-8 Omics on bioleaching: current and future impacts [Elektronische Daten] [Patricio Martinez, Mario Vera, Roberto Bobadilla-Fazzini] Bioleaching corresponds to the microbial-catalyzed process of conversion of insoluble metals into soluble forms. As an applied biotechnology globally used, it represents an extremely interesting field of research where omics techniques can be applied in terms of knowledge development, but moreover in terms of process design, control, and optimization. In this mini-review, the current state of genomics, proteomics, and metabolomics of bioleaching and the major impacts of these analytical methods at industrial scale are highlighted. In summary, genomics has been essential in the determination of the biodiversity of leaching processes and for development of conceptual and functional metabolic models. Proteomic impacts are mostly related to microbe-mineral interaction analysis, including copper resistance and biofilm formation. Early steps of metabolomics in the field of bioleaching have shown a significant potential for the use of metabolites as industrial biomarkers. Development directions are given in order to enhance the future impacts of the omics in biohydrometallurgy. The Author(s), 2015 Bioleaching nationallicence Genomics nationallicence Proteomics nationallicence Metabolomics nationallicence Martinez Patricio BioSigma ‘S.A.', Parque Industrial Los Libertadores, Lote 106, Colina, Chile aut Vera Mario Biofilm Centre, Aquatische Biotechnologie, Universität Duisburg-Essen, Universitätstraße 5, 45141, Essen, Germany aut Bobadilla-Fazzini Roberto BioSigma ‘S.A.', Parque Industrial Los Libertadores, Lote 106, Colina, Chile aut Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/20(2015-10-01), 8337-8350 0175-7598 99:20<8337 2015 99 253 https://doi.org/10.1007/s00253-015-6903-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00253-015-6903-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Martinez Patricio BioSigma ‘S.A.', Parque Industrial Los Libertadores, Lote 106, Colina, Chile aut NATIONALLICENCE 700 1- Vera Mario Biofilm Centre, Aquatische Biotechnologie, Universität Duisburg-Essen, Universitätstraße 5, 45141, Essen, Germany aut NATIONALLICENCE 700 1- Bobadilla-Fazzini Roberto BioSigma ‘S.A.', Parque Industrial Los Libertadores, Lote 106, Colina, Chile aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/20(2015-10-01), 8337-8350 0175-7598 99:20<8337 2015 99 253