Effect of 1,3-propanediol, organic acids, and ethanol on growth and metabolism of Clostridium butyricum DSP1
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| 024 | 7 | 0 | |a 10.1007/s00253-014-6292-4 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00253-014-6292-4 | ||
| 245 | 0 | 0 | |a Effect of 1,3-propanediol, organic acids, and ethanol on growth and metabolism of Clostridium butyricum DSP1 |h [Elektronische Daten] |c [Daria Szymanowska-Powałowska, Piotr Kubiak] |
| 520 | 3 | |a Knowledge of tolerance of bacteria to toxic stress is important, especially for processes targeted at high final titers of product. Information on environmental limits and stress responses may help during selection of strains or design and control of processes. The influence of the main product and its co-products on the process of 1,3-propanediol (PD) synthesis was determined. Adaptation to toxic compounds was noticed as Clostridium butyricum DSP1 was less sensitive to the addition of these factors during its exponential growth on glycerol than when the factor was present in the medium before inoculation. It was also shown that the response of the tested strain to the toxicity of 1,3-propanediol (1,3-PD) has different proteomic profiles depending on the stage of culture when this substance is introduced. Relatively satisfactory activity of the analyzed strain was sustained up to a concentration of 1,3-PD of 40g/L while 80g/L of this metabolite was lethal to the bacterium. As for the by-products, acetic acid was determined to be the most toxic among the acids excreted during the process. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2014 | ||
| 690 | 7 | |a Clostridium butyricum |2 nationallicence | |
| 690 | 7 | |a Environmental stress |2 nationallicence | |
| 690 | 7 | |a Ethanol |2 nationallicence | |
| 690 | 7 | |a Organic acids |2 nationallicence | |
| 690 | 7 | |a 1,3-Propanediol |2 nationallicence | |
| 700 | 1 | |a Szymanowska-Powałowska |D Daria |u Department of Biotechnology and Food Microbiology, Poznan University of Life Sciences, Wojska Polskiego 48, 60-527, Poznan, Poland |4 aut | |
| 700 | 1 | |a Kubiak |D Piotr |u Department of Biotechnology and Food Microbiology, Poznan University of Life Sciences, Wojska Polskiego 48, 60-527, Poznan, Poland |4 aut | |
| 773 | 0 | |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/7(2015-04-01), 3179-3189 |x 0175-7598 |q 99:7<3179 |1 2015 |2 99 |o 253 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00253-014-6292-4 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00253-014-6292-4 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Szymanowska-Powałowska |D Daria |u Department of Biotechnology and Food Microbiology, Poznan University of Life Sciences, Wojska Polskiego 48, 60-527, Poznan, Poland |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kubiak |D Piotr |u Department of Biotechnology and Food Microbiology, Poznan University of Life Sciences, Wojska Polskiego 48, 60-527, Poznan, Poland |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/7(2015-04-01), 3179-3189 |x 0175-7598 |q 99:7<3179 |1 2015 |2 99 |o 253 | ||