Recent research progress on microbial l -asparaginases
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| 024 | 7 | 0 | |a 10.1007/s00253-014-6271-9 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00253-014-6271-9 | ||
| 245 | 0 | 0 | |a Recent research progress on microbial l -asparaginases |h [Elektronische Daten] |c [Shaohua Zuo, Tao Zhang, Bo Jiang, Wanmeng Mu] |
| 520 | 3 | |a l-Asparaginases (EC 3.5.1.1) are enzymes that catalyze the hydrolysis of l-asparagine to l-aspartic acid and found in a variety of organisms from microorganisms to mammals. However, they are mainly expressed and produced by microorganisms. Microbial l-asparaginases have received sustained attention due to their irreplaceable role in the therapy of acute lymphoblastic leukemia and for their inhibition of acrylamide formation during food processing. In this article, we review the application of microbial l-asparaginases in medical treatments and acrylamide mitigation. In addition, we describe in detail recent advances in the existing sources, purification, production, properties, molecular modification, and immobilization of l-asparaginase. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2014 | ||
| 690 | 7 | |a l -Asparaginase |2 nationallicence | |
| 690 | 7 | |a Acute lymphoblastic leukemia |2 nationallicence | |
| 690 | 7 | |a Acrylamide |2 nationallicence | |
| 690 | 7 | |a Production |2 nationallicence | |
| 690 | 7 | |a Modification |2 nationallicence | |
| 690 | 7 | |a Immobilization |2 nationallicence | |
| 700 | 1 | |a Zuo |D Shaohua |u State Key Laboratory of Food Science and Technology, Ministry of Education Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China |4 aut | |
| 700 | 1 | |a Zhang |D Tao |u State Key Laboratory of Food Science and Technology, Ministry of Education Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China |4 aut | |
| 700 | 1 | |a Jiang |D Bo |u State Key Laboratory of Food Science and Technology, Ministry of Education Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China |4 aut | |
| 700 | 1 | |a Mu |D Wanmeng |u State Key Laboratory of Food Science and Technology, Ministry of Education Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China |4 aut | |
| 773 | 0 | |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/3(2015-02-01), 1069-1079 |x 0175-7598 |q 99:3<1069 |1 2015 |2 99 |o 253 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00253-014-6271-9 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a review-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00253-014-6271-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zuo |D Shaohua |u State Key Laboratory of Food Science and Technology, Ministry of Education Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zhang |D Tao |u State Key Laboratory of Food Science and Technology, Ministry of Education Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Jiang |D Bo |u State Key Laboratory of Food Science and Technology, Ministry of Education Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mu |D Wanmeng |u State Key Laboratory of Food Science and Technology, Ministry of Education Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, 214122, Wuxi, Jiangsu, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/3(2015-02-01), 1069-1079 |x 0175-7598 |q 99:3<1069 |1 2015 |2 99 |o 253 | ||