16S rRNA gene high-throughput sequencing data mining of microbial diversity and interactions

Verfasser / Beitragende:
[Feng Ju, Tong Zhang]
Ort, Verlag, Jahr:
2015
Enthalten in:
Applied Microbiology and Biotechnology, 99/10(2015-05-01), 4119-4129
Format:
Artikel (online)
ID: 605501998
LEADER caa a22 4500
001 605501998
003 CHVBK
005 20210128100603.0
007 cr unu---uuuuu
008 210128e20150501xx s 000 0 eng
024 7 0 |a 10.1007/s00253-015-6536-y  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00253-015-6536-y 
245 0 0 |a 16S rRNA gene high-throughput sequencing data mining of microbial diversity and interactions  |h [Elektronische Daten]  |c [Feng Ju, Tong Zhang] 
520 3 |a The ubiquitous occurrence of microorganisms gives rise to continuous public concerns regarding their pathogenicity and threats to human environment, as well as potential engineering benefits in biotechnology. The development and wide application of environmental biotechnology, for example in bioenergy production, wastewater treatment, bioremediation, and drinking water disinfection, have been bringing us with both environmental and economic benefits. Strikingly, extensive applications of microscopic and molecular techniques since 1990s have allowed engineers to peep into the microbiology in "black box” of engineered microbial communities in biotechnological processes, providing guidelines for process design and optimization. Recently, revolutionary advances in DNA sequencing technologies and rapidly decreasing costs are altering conventional ways of microbiology and ecology research, as it launches an era of next-generation sequencing (NGS). The principal research burdens are now transforming from traditional labor-intensive wet-lab experiments to dealing with analysis of huge and informative NGS data, which is computationally expensive and bioinformatically challenging. This study discusses state-of-the-art bioinformatics and statistical analyses of 16S ribosomal RNA (rRNA) gene high-throughput sequencing (HTS) data from prevalent NGS platforms to promote its applications in exploring microbial diversity of functional and pathogenic microorganisms, as well as their interactions in biotechnological processes. 
540 |a Springer-Verlag Berlin Heidelberg, 2015 
690 7 |a Next-generation sequencing  |2 nationallicence 
690 7 |a 16S rRNA gene  |2 nationallicence 
690 7 |a Bioinformatics and statistics  |2 nationallicence 
690 7 |a Network analysis  |2 nationallicence 
690 7 |a Microbiology  |2 nationallicence 
690 7 |a Biotechnology  |2 nationallicence 
700 1 |a Ju  |D Feng  |u Environmental Biotechnology Lab, The University of Hong Kong, Pokfulam Road, Hong Kong, China  |4 aut 
700 1 |a Zhang  |D Tong  |u Environmental Biotechnology Lab, The University of Hong Kong, Pokfulam Road, Hong Kong, China  |4 aut 
773 0 |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/10(2015-05-01), 4119-4129  |x 0175-7598  |q 99:10<4119  |1 2015  |2 99  |o 253 
856 4 0 |u https://doi.org/10.1007/s00253-015-6536-y  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00253-015-6536-y  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ju  |D Feng  |u Environmental Biotechnology Lab, The University of Hong Kong, Pokfulam Road, Hong Kong, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zhang  |D Tong  |u Environmental Biotechnology Lab, The University of Hong Kong, Pokfulam Road, Hong Kong, China  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/10(2015-05-01), 4119-4129  |x 0175-7598  |q 99:10<4119  |1 2015  |2 99  |o 253