Proteins, peptides, polysaccharides, and nucleotides with inhibitory activity on human immunodeficiency virus and its enzymes

Verfasser / Beitragende:
[Tzi Ng, Randy Cheung, Jack Wong, Wai Chan]
Ort, Verlag, Jahr:
2015
Enthalten in:
Applied Microbiology and Biotechnology, 99/24(2015-12-01), 10399-10414
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00253-015-6997-z  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00253-015-6997-z 
245 0 0 |a Proteins, peptides, polysaccharides, and nucleotides with inhibitory activity on human immunodeficiency virus and its enzymes  |h [Elektronische Daten]  |c [Tzi Ng, Randy Cheung, Jack Wong, Wai Chan] 
520 3 |a Human immunodeficiency virus (HIV), the causative agent of acquired immune deficiency syndrome, has claimed innumerable lives in the past. Many biomolecules which suppress HIV replication and also other biomolecules that inhibit enzymes essential to HIV replication have been reported. Proteins including a variety of milk proteins, ribosome-inactivating proteins, ribonucleases, antifungal proteins, and trypsin inhibitors; peptides comprising cathelicidins, defensins, synthetic peptides, and others; polysaccharides and polysaccharopeptides; nucleosides, nucleotides, and ribozymes, demonstrated anti-HIV activity. In many cases, the mechanism of anti-HIV action has been elucidated. Strategies have been devised to augment the anti-HIV potency of these compounds. 
540 |a Springer-Verlag Berlin Heidelberg, 2015 
690 7 |a Anti-HIV  |2 nationallicence 
690 7 |a Proteins  |2 nationallicence 
690 7 |a Peptides  |2 nationallicence 
690 7 |a Polysaccharides  |2 nationallicence 
690 7 |a Ribozymes  |2 nationallicence 
690 7 |a Nucleic acids  |2 nationallicence 
700 1 |a Ng  |D Tzi  |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, New Territories, China  |4 aut 
700 1 |a Cheung  |D Randy  |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, New Territories, China  |4 aut 
700 1 |a Wong  |D Jack  |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, New Territories, China  |4 aut 
700 1 |a Chan  |D Wai  |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, New Territories, China  |4 aut 
773 0 |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/24(2015-12-01), 10399-10414  |x 0175-7598  |q 99:24<10399  |1 2015  |2 99  |o 253 
856 4 0 |u https://doi.org/10.1007/s00253-015-6997-z  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ng  |D Tzi  |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, New Territories, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Cheung  |D Randy  |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, New Territories, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wong  |D Jack  |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, New Territories, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chan  |D Wai  |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, New Territories, China  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/24(2015-12-01), 10399-10414  |x 0175-7598  |q 99:24<10399  |1 2015  |2 99  |o 253