CYP287A1 is a carotenoid 2-β-hydroxylase required for deinoxanthin biosynthesis in Deinococcus radiodurans R1
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| 008 | 210128e20151201xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00253-015-6910-9 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00253-015-6910-9 | ||
| 245 | 0 | 0 | |a CYP287A1 is a carotenoid 2-β-hydroxylase required for deinoxanthin biosynthesis in Deinococcus radiodurans R1 |h [Elektronische Daten] |c [Zhengfu Zhou, Wei Zhang, Shiyou Su, Ming Chen, Wei Lu, Min Lin, István Molnár, Yuquan Xu] |
| 520 | 3 | |a The carotenoid deinoxanthin is a crucial resistance factor against various stresses in the radiation-resistant bacterium Deinococcus radiodurans. Disruption of the gene dr2473 encoding the cytochrome P450 CYP287A1 led to the accumulation of 2-deoxydeinoxanthin in D. radiodurans, demonstrating that CYP287A1 is a novel β-carotene 2-hydroxylase. The dr2473 knockout mutant was shown to be more sensitive to UV radiation and oxidative stress than the wild-type strain D. radiodurans R1, indicating that the C2 alcohol of deinoxanthin is important for antioxidant activity. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2015 | ||
| 690 | 7 | |a Deinococcus radiodurans |2 nationallicence | |
| 690 | 7 | |a Deinoxanthin |2 nationallicence | |
| 690 | 7 | |a CYP287A1 |2 nationallicence | |
| 690 | 7 | |a Cytochrome P450 |2 nationallicence | |
| 690 | 7 | |a 2-β-hydroxylase |2 nationallicence | |
| 700 | 1 | |a Zhou |D Zhengfu |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | |
| 700 | 1 | |a Zhang |D Wei |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | |
| 700 | 1 | |a Su |D Shiyou |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | |
| 700 | 1 | |a Chen |D Ming |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | |
| 700 | 1 | |a Lu |D Wei |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | |
| 700 | 1 | |a Lin |D Min |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | |
| 700 | 1 | |a Molnár |D István |u Natural Products Center, School of Natural Resources and the Environment, University of Arizona, 85706, Tucson, AZ, USA |4 aut | |
| 700 | 1 | |a Xu |D Yuquan |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | |
| 773 | 0 | |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/24(2015-12-01), 10539-10546 |x 0175-7598 |q 99:24<10539 |1 2015 |2 99 |o 253 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00253-015-6910-9 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00253-015-6910-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zhou |D Zhengfu |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zhang |D Wei |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Su |D Shiyou |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chen |D Ming |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lu |D Wei |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lin |D Min |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Molnár |D István |u Natural Products Center, School of Natural Resources and the Environment, University of Arizona, 85706, Tucson, AZ, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Xu |D Yuquan |u Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, People's Republic of China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/24(2015-12-01), 10539-10546 |x 0175-7598 |q 99:24<10539 |1 2015 |2 99 |o 253 | ||