Antiviral activities of whey proteins
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| 024 | 7 | 0 | |a 10.1007/s00253-015-6818-4 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00253-015-6818-4 | ||
| 245 | 0 | 0 | |a Antiviral activities of whey proteins |h [Elektronische Daten] |c [Tzi Ng, Randy Cheung, Jack Wong, Yan Wang, Denis Ip, David Wan, Jiang Xia] |
| 520 | 3 | |a Milk contains an array of proteins with useful bioactivities. Many milk proteins encompassing native or chemically modified casein, lactoferrin, alpha-lactalbumin, and beta-lactoglobulin demonstrated antiviral activities. Casein and alpha-lactalbumin gained anti-HIV activity after modification with 3-hydroxyphthalic anhydride. Many milk proteins inhibited HIV reverse transcriptase. Bovine glycolactin, angiogenin-1, lactogenin, casein, alpha-lactalbumin, beta-lactoglobulin, bovine lactoferrampin, and human lactoferrampin inhibited HIV-1 protease and integrase. Several mammalian lactoferrins prevented hepatitis C infection. Lactoferrin, methylated alpha-lactalbumin and methylated beta-lactoglobulin inhibited human cytomegalovirus. Chemically modified alpha-lactalbumin, beta-lactoglobulin and lysozyme, lactoferrin and lactoferricin, methylated alpha-lactalbumin, methylated and ethylated beta-lactoglobulins inhibited HSV. Chemically modified bovine beta-lactoglobulin had antihuman papillomavirus activity. Beta-lactoglobulin, lactoferrin, esterified beta-lactoglobulin, and esterified lactoferrindisplayed anti-avian influenza A (H5N1) activity. Lactoferrin inhibited respiratory syncytial virus, hepatitis B virus, adenovirus, poliovirus, hantavirus, sindbis virus, semliki forest virus, echovirus, and enterovirus. Milk mucin, apolactoferrin, Fe3+-lactoferrin, beta-lactoglobulin, human lactadherin, bovine IgG, and bovine kappa-casein demonstrated antihuman rotavirus activity. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2015 | ||
| 690 | 7 | |a Whey proteins |2 nationallicence | |
| 690 | 7 | |a Antiviral |2 nationallicence | |
| 690 | 7 | |a Lactoferrin |2 nationallicence | |
| 690 | 7 | |a Lactalbumin |2 nationallicence | |
| 690 | 7 | |a Lactoglobulin |2 nationallicence | |
| 690 | 7 | |a Lysozyme |2 nationallicence | |
| 700 | 1 | |a Ng |D Tzi |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | |
| 700 | 1 | |a Cheung |D Randy |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | |
| 700 | 1 | |a Wong |D Jack |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | |
| 700 | 1 | |a Wang |D Yan |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | |
| 700 | 1 | |a Ip |D Denis |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | |
| 700 | 1 | |a Wan |D David |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | |
| 700 | 1 | |a Xia |D Jiang |u Department of Chemistry, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, China |4 aut | |
| 773 | 0 | |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/17(2015-09-01), 6997-7008 |x 0175-7598 |q 99:17<6997 |1 2015 |2 99 |o 253 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00253-015-6818-4 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a review-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00253-015-6818-4 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ng |D Tzi |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cheung |D Randy |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wong |D Jack |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wang |D Yan |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ip |D Denis |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wan |D David |u School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Xia |D Jiang |u Department of Chemistry, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/17(2015-09-01), 6997-7008 |x 0175-7598 |q 99:17<6997 |1 2015 |2 99 |o 253 | ||