caa a22 4500 605502870 CHVBK 20210128100608.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00253-015-6806-8 doi (NATIONALLICENCE)springer-10.1007/s00253-015-6806-8 Production of ginseng saponins: elicitation strategy and signal transductions [Elektronische Daten] [Shadi Rahimi, Yu-Jin Kim, Deok-Chun Yang] Ginseng is one of the most important plants in oriental medicine. The pharmacological effects of this medicinal herb are mostly correlated to the major bioactive triterpene saponin, called ginsenoside. Due to the long cultivation period of ginseng and increased ginsenoside level in aged root, we need to develop strategies to increase ginseng productivity in cell and tissue culture in a faster way. Elicitation is already considered to improve the yield of this valuable secondary metabolite; especially, different types, timings, and durations of elicitationcould affect the ginsenoside production and heterogeneity. Activation of ginsenoside biosynthetic genes and ginsenoside accumulation mediated by elicitor-induced signaling molecules would be helpful for commercial production of individual ginsenosides. Jasmonic acid is the well-known signaling molecule which mainly involved in ginsenoside accumulation. Ca2+ spiking and reactive oxygen species, nitric oxide, and ethylene production are other messengers which mediate production of ginsenoside. This review highlights the elicitation strategies for production of the ginsenoside based on the principle of putative signal transduction pathways. Springer-Verlag Berlin Heidelberg, 2015 Elicitation nationallicence Ginsenoside nationallicence Ginseng nationallicence Jasmonic acid nationallicence Signal transduction nationallicence Rahimi Shadi Graduate School of Biotechnology and Ginseng Bank, College of Life Sciences, Kyung Hee University, 446-701, Yongin, Republic of Korea aut Kim Yu-Jin Department of Oriental Medicinal Biotechnology, College of Life Sciences, Kyung Hee University, 446-701, Yongin, Republic of Korea aut Yang Deok-Chun Graduate School of Biotechnology and Ginseng Bank, College of Life Sciences, Kyung Hee University, 446-701, Yongin, Republic of Korea aut Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/17(2015-09-01), 6987-6996 0175-7598 99:17<6987 2015 99 253 https://doi.org/10.1007/s00253-015-6806-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00253-015-6806-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rahimi Shadi Graduate School of Biotechnology and Ginseng Bank, College of Life Sciences, Kyung Hee University, 446-701, Yongin, Republic of Korea aut NATIONALLICENCE 700 1- Kim Yu-Jin Department of Oriental Medicinal Biotechnology, College of Life Sciences, Kyung Hee University, 446-701, Yongin, Republic of Korea aut NATIONALLICENCE 700 1- Yang Deok-Chun Graduate School of Biotechnology and Ginseng Bank, College of Life Sciences, Kyung Hee University, 446-701, Yongin, Republic of Korea aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/17(2015-09-01), 6987-6996 0175-7598 99:17<6987 2015 99 253