Recent applications of Vitreoscilla hemoglobin technology in bioproduct synthesis and bioremediation

Verfasser / Beitragende:
[Benjamin Stark, Krishna Pagilla, Kanak Dikshit]
Ort, Verlag, Jahr:
2015
Enthalten in:
Applied Microbiology and Biotechnology, 99/4(2015-02-01), 1627-1636
Format:
Artikel (online)
ID: 605503680
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024 7 0 |a 10.1007/s00253-014-6350-y  |2 doi 
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245 0 0 |a Recent applications of Vitreoscilla hemoglobin technology in bioproduct synthesis and bioremediation  |h [Elektronische Daten]  |c [Benjamin Stark, Krishna Pagilla, Kanak Dikshit] 
520 3 |a Since its first use in 1990 to enhance production of α-amylase in E. coli, engineering of heterologous hosts to express the hemoglobin from the bacterium Vitreoscilla (VHb) has become a widely used strategy to enhance production of a variety of bioproducts, stimulate bioremediation, and increase growth and survival of engineered organisms. The hosts have included a variety of bacteria, yeast, fungi, higher plants, and even animals. The beneficial effects of VHb expression are presumably the result of one or more of its activities. The available evidence indicates that these include oxygen binding and delivery to the respiratory chain and oxygenases, protection against reactive oxygen species, and control of gene expression. In the past 4 to 5years, the use of this "VHb technology” has continued in a variety of biotechnological applications in a wide range of organisms. These include enhancement of production of an ever wider array of bioproducts, new applications in bioremediation, a possible role in enhancing aerobic waste water treatment, and the potential to enhance growth and survival of both plants and animals of economic importance. 
540 |a Springer-Verlag Berlin Heidelberg, 2015 
690 7 |a Bioproducts  |2 nationallicence 
690 7 |a Bioremediation  |2 nationallicence 
690 7 |a Genetic engineering  |2 nationallicence 
690 7 |a Vitreoscilla hemoglobin  |2 nationallicence 
690 7 |a Waste water  |2 nationallicence 
700 1 |a Stark  |D Benjamin  |u Biology Division, Department of Biological and Chemical Sciences, Illinois Institute of Technology, 60616, Chicago, IL, USA  |4 aut 
700 1 |a Pagilla  |D Krishna  |u Department of Civil, Architectural, and Environmental Engineering, Illinois Institute of Technology, 60616, Chicago, IL, USA  |4 aut 
700 1 |a Dikshit  |D Kanak  |u Institute of Microbial Technology, Sec-39a, 160036, Chandigarh, India  |4 aut 
773 0 |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/4(2015-02-01), 1627-1636  |x 0175-7598  |q 99:4<1627  |1 2015  |2 99  |o 253 
856 4 0 |u https://doi.org/10.1007/s00253-014-6350-y  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Stark  |D Benjamin  |u Biology Division, Department of Biological and Chemical Sciences, Illinois Institute of Technology, 60616, Chicago, IL, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pagilla  |D Krishna  |u Department of Civil, Architectural, and Environmental Engineering, Illinois Institute of Technology, 60616, Chicago, IL, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Dikshit  |D Kanak  |u Institute of Microbial Technology, Sec-39a, 160036, Chandigarh, India  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/4(2015-02-01), 1627-1636  |x 0175-7598  |q 99:4<1627  |1 2015  |2 99  |o 253