Methylobacterium extorquens
methylotrophy and biotechnological applications
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| 024 | 7 | 0 | |a 10.1007/s00253-014-6240-3 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00253-014-6240-3 | ||
| 245 | 0 | 0 | |a Methylobacterium extorquens |h [Elektronische Daten] |b methylotrophy and biotechnological applications |c [Andrea Ochsner, Frank Sonntag, Markus Buchhaupt, Jens Schrader, Julia Vorholt] |
| 520 | 3 | |a Methylotrophy is the ability to use reduced one-carbon compounds, such as methanol, as a single source of carbon and energy. Methanol is, due to its availability and potential for production from renewable resources, a valuable feedstock for biotechnology. Nature offers a variety of methylotrophic microorganisms that differ in their metabolism and represent resources for engineering of value-added products from methanol. The most extensively studied methylotroph is the Alphaproteobacterium Methylobacterium extorquens. Over the past five decades, the metabolism of M. extorquens has been investigated physiologically, biochemically, and more recently, using complementary omics technologies such as transcriptomics, proteomics, metabolomics, and fluxomics. These approaches, together with a genome-scale metabolic model, facilitate system-wide studies and the development of rational strategies for the successful generation of desired products from methanol. This review summarizes the knowledge of methylotrophy in M. extorquens, as well as the available tools and biotechnological applications. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2014 | ||
| 690 | 7 | |a Methylobacterium extorquens |2 nationallicence | |
| 690 | 7 | |a Methanol |2 nationallicence | |
| 690 | 7 | |a Methylotrophy |2 nationallicence | |
| 690 | 7 | |a Industrial biotechnology |2 nationallicence | |
| 700 | 1 | |a Ochsner |D Andrea |u Institute of Microbiology, ETH Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland |4 aut | |
| 700 | 1 | |a Sonntag |D Frank |u DECHEMA Forschungsinstitut, Theodor-Heuss-Allee 25, 60486, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Buchhaupt |D Markus |u DECHEMA Forschungsinstitut, Theodor-Heuss-Allee 25, 60486, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Schrader |D Jens |u DECHEMA Forschungsinstitut, Theodor-Heuss-Allee 25, 60486, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Vorholt |D Julia |u Institute of Microbiology, ETH Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland |4 aut | |
| 773 | 0 | |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/2(2015-01-01), 517-534 |x 0175-7598 |q 99:2<517 |1 2015 |2 99 |o 253 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00253-014-6240-3 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a review-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00253-014-6240-3 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ochsner |D Andrea |u Institute of Microbiology, ETH Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sonntag |D Frank |u DECHEMA Forschungsinstitut, Theodor-Heuss-Allee 25, 60486, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Buchhaupt |D Markus |u DECHEMA Forschungsinstitut, Theodor-Heuss-Allee 25, 60486, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Schrader |D Jens |u DECHEMA Forschungsinstitut, Theodor-Heuss-Allee 25, 60486, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vorholt |D Julia |u Institute of Microbiology, ETH Zurich, Vladimir-Prelog-Weg 4, 8093, Zurich, Switzerland |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/2(2015-01-01), 517-534 |x 0175-7598 |q 99:2<517 |1 2015 |2 99 |o 253 | ||