A jack-of-all-trades: 2-mercaptosuccinic acid

Verfasser / Beitragende:
[Ulrike Brandt, Anika Deters, Alexander Steinbüchel]
Ort, Verlag, Jahr:
2015
Enthalten in:
Applied Microbiology and Biotechnology, 99/11(2015-06-01), 4545-4557
Format:
Artikel (online)
ID: 605506280
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024 7 0 |a 10.1007/s00253-015-6605-2  |2 doi 
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245 0 2 |a A jack-of-all-trades: 2-mercaptosuccinic acid  |h [Elektronische Daten]  |c [Ulrike Brandt, Anika Deters, Alexander Steinbüchel] 
520 3 |a 2-Mercaptosuccinic acid (MS) is an important and versatile substance for diverse fields of applications of which the most significant are surveyed in this article. Biological, chemical, and physical properties of MS as well as the knowledge of its synthesis and microbial degradation are illustrated. In addition, exemplary structural analogs of the organic sulfur compound are commented. The key application of MS in nanotechnology is discussed in detail with particular emphasis on quantum dots (nanocrystals) and self-assembled monolayers in combination with gold or silver. Furthermore, some medical and pharmaceutical applications are given, inter alia in bioimaging, as a nanocarrier, and with regard to the antimicrobial activity of MS-silver and MS-gold nanoparticles. Moreover, biological and chemical applications of MS are exemplified: the thiol compound can serve as an inhibitor for glutathione peroxidase, or the toxicity of substances can be increased due to the presence of MS in the respective cells or tissues. In the field of cosmetics, MS is widely utilized as a reducing agent for numerous products as explained in this article. Additionally, the microbial utilization of MS as a carbon and energy source for growth is elucidated in-depth, providing insight into different catabolic mechanisms. 
540 |a Springer-Verlag Berlin Heidelberg, 2015 
690 7 |a Mercaptosuccinate  |2 nationallicence 
690 7 |a Nanotechnology  |2 nationallicence 
690 7 |a Quantum dots  |2 nationallicence 
690 7 |a Variovorax paradoxus  |2 nationallicence 
700 1 |a Brandt  |D Ulrike  |u Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany  |4 aut 
700 1 |a Deters  |D Anika  |u Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany  |4 aut 
700 1 |a Steinbüchel  |D Alexander  |u Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany  |4 aut 
773 0 |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/11(2015-06-01), 4545-4557  |x 0175-7598  |q 99:11<4545  |1 2015  |2 99  |o 253 
856 4 0 |u https://doi.org/10.1007/s00253-015-6605-2  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Brandt  |D Ulrike  |u Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Deters  |D Anika  |u Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Steinbüchel  |D Alexander  |u Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/11(2015-06-01), 4545-4557  |x 0175-7598  |q 99:11<4545  |1 2015  |2 99  |o 253