caa a22 4500 605506280 CHVBK 20210128100626.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00253-015-6605-2 doi (NATIONALLICENCE)springer-10.1007/s00253-015-6605-2 A jack-of-all-trades: 2-mercaptosuccinic acid [Elektronische Daten] [Ulrike Brandt, Anika Deters, Alexander Steinbüchel] 2-Mercaptosuccinic acid (MS) is an important and versatile substance for diverse fields of applications of which the most significant are surveyed in this article. Biological, chemical, and physical properties of MS as well as the knowledge of its synthesis and microbial degradation are illustrated. In addition, exemplary structural analogs of the organic sulfur compound are commented. The key application of MS in nanotechnology is discussed in detail with particular emphasis on quantum dots (nanocrystals) and self-assembled monolayers in combination with gold or silver. Furthermore, some medical and pharmaceutical applications are given, inter alia in bioimaging, as a nanocarrier, and with regard to the antimicrobial activity of MS-silver and MS-gold nanoparticles. Moreover, biological and chemical applications of MS are exemplified: the thiol compound can serve as an inhibitor for glutathione peroxidase, or the toxicity of substances can be increased due to the presence of MS in the respective cells or tissues. In the field of cosmetics, MS is widely utilized as a reducing agent for numerous products as explained in this article. Additionally, the microbial utilization of MS as a carbon and energy source for growth is elucidated in-depth, providing insight into different catabolic mechanisms. Springer-Verlag Berlin Heidelberg, 2015 Mercaptosuccinate nationallicence Nanotechnology nationallicence Quantum dots nationallicence Variovorax paradoxus nationallicence Brandt Ulrike Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany aut Deters Anika Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany aut Steinbüchel Alexander Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany aut Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/11(2015-06-01), 4545-4557 0175-7598 99:11<4545 2015 99 253 https://doi.org/10.1007/s00253-015-6605-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00253-015-6605-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Brandt Ulrike Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany aut NATIONALLICENCE 700 1- Deters Anika Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany aut NATIONALLICENCE 700 1- Steinbüchel Alexander Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität, Corrensstraße 3, D-48149, Münster, Germany aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/11(2015-06-01), 4545-4557 0175-7598 99:11<4545 2015 99 253