Yarrowia lipolytica

recent achievements in heterologous protein expression and pathway engineering

Verfasser / Beitragende:
[Catherine Madzak]
Ort, Verlag, Jahr:
2015
Enthalten in:
Applied Microbiology and Biotechnology, 99/11(2015-06-01), 4559-4577
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00253-015-6624-z  |2 doi 
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100 1 |a Madzak  |D Catherine  |u INRA, UMR1319, Micalis Institute, AgroParisTech campus, CBAI, F-78850, Thiverval-Grignon, France  |4 aut 
245 1 0 |a Yarrowia lipolytica  |h [Elektronische Daten]  |b recent achievements in heterologous protein expression and pathway engineering  |c [Catherine Madzak] 
520 3 |a The oleaginous yeast Yarrowia lipolytica has become a recognized system for expression/secretion of heterologous proteins. This non-conventional yeast is currently being developed as a workhorse for biotechnology by several research groups throughout the world, especially for single-cell oil production, whole cell bioconversion and upgrading of industrial wastes. This mini-review presents established tools for protein expression in Y. lipolytica and highlights novel developments in the areas of promoter design, surface display, and host strain or metabolic pathway engineering. An overview of the industrial and commercial biotechnological applications of Y. lipolytica is also presented. 
540 |a Springer-Verlag Berlin Heidelberg, 2015 
690 7 |a Yarrowia lipolytica  |2 nationallicence 
690 7 |a Oleaginous yeast  |2 nationallicence 
690 7 |a Heterologous protein  |2 nationallicence 
690 7 |a Expression  |2 nationallicence 
690 7 |a Secretion  |2 nationallicence 
690 7 |a Surface display  |2 nationallicence 
690 7 |a Genetic engineering  |2 nationallicence 
690 7 |a Biotechnology  |2 nationallicence 
690 7 |a Lipid metabolism  |2 nationallicence 
773 0 |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/11(2015-06-01), 4559-4577  |x 0175-7598  |q 99:11<4559  |1 2015  |2 99  |o 253 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
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950 |B NATIONALLICENCE  |P 100  |E 1-  |a Madzak  |D Catherine  |u INRA, UMR1319, Micalis Institute, AgroParisTech campus, CBAI, F-78850, Thiverval-Grignon, France  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Applied Microbiology and Biotechnology  |d Springer Berlin Heidelberg  |g 99/11(2015-06-01), 4559-4577  |x 0175-7598  |q 99:11<4559  |1 2015  |2 99  |o 253