caa a22 4500 605506345 CHVBK 20210128100626.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00253-015-6624-z doi (NATIONALLICENCE)springer-10.1007/s00253-015-6624-z Madzak Catherine INRA, UMR1319, Micalis Institute, AgroParisTech campus, CBAI, F-78850, Thiverval-Grignon, France aut Yarrowia lipolytica [Elektronische Daten] recent achievements in heterologous protein expression and pathway engineering [Catherine Madzak] The oleaginous yeast Yarrowia lipolytica has become a recognized system for expression/secretion of heterologous proteins. This non-conventional yeast is currently being developed as a workhorse for biotechnology by several research groups throughout the world, especially for single-cell oil production, whole cell bioconversion and upgrading of industrial wastes. This mini-review presents established tools for protein expression in Y. lipolytica and highlights novel developments in the areas of promoter design, surface display, and host strain or metabolic pathway engineering. An overview of the industrial and commercial biotechnological applications of Y. lipolytica is also presented. Springer-Verlag Berlin Heidelberg, 2015 Yarrowia lipolytica nationallicence Oleaginous yeast nationallicence Heterologous protein nationallicence Expression nationallicence Secretion nationallicence Surface display nationallicence Genetic engineering nationallicence Biotechnology nationallicence Lipid metabolism nationallicence Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/11(2015-06-01), 4559-4577 0175-7598 99:11<4559 2015 99 253 https://doi.org/10.1007/s00253-015-6624-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00253-015-6624-z text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Madzak Catherine INRA, UMR1319, Micalis Institute, AgroParisTech campus, CBAI, F-78850, Thiverval-Grignon, France aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer Berlin Heidelberg 99/11(2015-06-01), 4559-4577 0175-7598 99:11<4559 2015 99 253