Structural diversity and possible functional roles of free fatty acids of the novel soil isolate Streptomyces sp. NP10
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| 024 | 7 | 0 | |a 10.1007/s00253-014-6364-5 |2 doi |
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| 245 | 0 | 0 | |a Structural diversity and possible functional roles of free fatty acids of the novel soil isolate Streptomyces sp. NP10 |h [Elektronische Daten] |c [Tatjana Ilic-Tomic, Marija Genčić, Milena Živković, Branka Vasiljevic, Lidija Djokic, Jasmina Nikodinovic-Runic, Niko Radulović] |
| 520 | 3 | |a Herein, a novel soil bacterium Streptomyces sp. NP10 able to grow outside usual streptomycetes optimum conditions (e.g., at 4°C, pH 9 and high NaCl concentration), exhibiting atypical hemolytic, DNAse, and cellulolytic activities, is described. This strain produces and excretes into the growth medium large amounts of free long-chain fatty acids (FAs). A concurrent lipidomics study revealed a large structural diversity of FAs with over 50 different n- and branched-chain, (un)saturated, and cyclopropane FAs (C7-C30) produced by this strain. Two of these, i-17:0cy9-10 and a-18:0cy9-10, represent new natural products and the first ever identified branched cyclopropane FAs. Both free and bound lipid profiles of Streptomyces sp. NP10 were dominated by saturated branched chain FAs (i-14:0, a-15:0, and i-16:0). Although these free FAs showed only a moderate antimicrobial activity, our results suggest that they could have an ecophysiological role in interspecies signaling with another soil microorganism Pseudomonas aeruginosa. This work represents the first comprehensive report on the structural diversity and complexity of the free FA pool in Streptomyces. A naturally occurring streptomycete, such as Streptomyces sp. NP10, which secretes significant amounts of free long-chain FAs (non-cytotoxic) into the medium, could be useful in microbial biodiesel production. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2015 | ||
| 690 | 7 | |a Streptomyces sp. NP10 |2 nationallicence | |
| 690 | 7 | |a Lipidomics |2 nationallicence | |
| 690 | 7 | |a Free fatty acids |2 nationallicence | |
| 690 | 7 | |a Branched cyclopropane fatty acids |2 nationallicence | |
| 690 | 7 | |a Ecophysiological role |2 nationallicence | |
| 690 | 7 | |a Microbial biodiesel production |2 nationallicence | |
| 700 | 1 | |a Ilic-Tomic |D Tatjana |u Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, 11010, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Genčić |D Marija |u Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia |4 aut | |
| 700 | 1 | |a Živković |D Milena |u Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia |4 aut | |
| 700 | 1 | |a Vasiljevic |D Branka |u Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, 11010, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Djokic |D Lidija |u Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, 11010, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Nikodinovic-Runic |D Jasmina |u Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, 11010, Belgrade, Serbia |4 aut | |
| 700 | 1 | |a Radulović |D Niko |u Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia |4 aut | |
| 773 | 0 | |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/11(2015-06-01), 4815-4833 |x 0175-7598 |q 99:11<4815 |1 2015 |2 99 |o 253 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00253-014-6364-5 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00253-014-6364-5 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ilic-Tomic |D Tatjana |u Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, 11010, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Genčić |D Marija |u Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Živković |D Milena |u Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vasiljevic |D Branka |u Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, 11010, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Djokic |D Lidija |u Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, 11010, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nikodinovic-Runic |D Jasmina |u Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, P.O. Box 23, 11010, Belgrade, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Radulović |D Niko |u Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Applied Microbiology and Biotechnology |d Springer Berlin Heidelberg |g 99/11(2015-06-01), 4815-4833 |x 0175-7598 |q 99:11<4815 |1 2015 |2 99 |o 253 | ||