Reactivity of hexanuclear ruthenium metallaprisms towards nucleotides and a DNA decamer
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| 024 | 7 | 0 | |a 10.1007/s00775-014-1208-4 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00775-014-1208-4 | ||
| 245 | 0 | 0 | |a Reactivity of hexanuclear ruthenium metallaprisms towards nucleotides and a DNA decamer |h [Elektronische Daten] |c [Lydia Paul, Bruno Therrien, Julien Furrer] |
| 520 | 3 | |a The reactivity of three hexacationic arene ruthenium metallaprisms towards isolated nucleotides and a short DNA strand was investigated using NMR spectroscopy, ESI mass spectrometry, UV/Vis and circular dichroism spectroscopy. The metallaprism built from oxalato-bridging ligands reacts rapidly in the presence of deoxyguanosine monophosphate (dGMP) and deoxyadenosine monophosphate, while the benzoquinonato derivative only reacts with dGMP. On the other hand, the larger metallaprism incorporating naphtoquinonato bridges remains stable in the presence of nucleotides. The reactivity of the three hexacationic metallaprisms with the decameric oligonucleotide d(CGCGATCGCG)2 was also investigated. Analysis of the NMR, MS, UV/Vis and CD data suggests that no adducts are formed between the oligonucleotide and the metallaprisms, but electrostatic interactions, leading to partial unwinding of the double-stranded oligonucleotide, were evidenced. | |
| 540 | |a SBIC, 2014 | ||
| 690 | 7 | |a Ruthenium |2 nationallicence | |
| 690 | 7 | |a Metallaprisms |2 nationallicence | |
| 690 | 7 | |a Nucleotides |2 nationallicence | |
| 690 | 7 | |a DNA interaction |2 nationallicence | |
| 690 | 7 | |a AA : Amino acid |2 nationallicence | |
| 690 | 7 | |a dhbq : 2,5-Dihydroxy-1,4-benzoquinonato |2 nationallicence | |
| 690 | 7 | |a dhnq : 5,8-Dihydroxy-1,4-naphthoquinonato |2 nationallicence | |
| 690 | 7 | |a DOSY : Diffusion-ordered spectroscopy |2 nationallicence | |
| 690 | 7 | |a ESI : Electrospray ionization |2 nationallicence | |
| 690 | 7 | |a oxa : Oxalato |2 nationallicence | |
| 690 | 7 | |a tpt : 2,4,6-Tri(pyridin-4-yl)-1,3,5-triazine |2 nationallicence | |
| 700 | 1 | |a Paul |D Lydia |u Departement für Chemie und Biochemie, Universität Bern, 3012, Bern, Switzerland |4 aut | |
| 700 | 1 | |a Therrien |D Bruno |u Institut de Chimie, Université de Neuchâtel, 2000, Neuchâtel, Switzerland |4 aut | |
| 700 | 1 | |a Furrer |D Julien |u Departement für Chemie und Biochemie, Universität Bern, 3012, Bern, Switzerland |4 aut | |
| 773 | 0 | |t JBIC Journal of Biological Inorganic Chemistry |d Springer Berlin Heidelberg |g 20/1(2015-01-01), 49-59 |x 0949-8257 |q 20:1<49 |1 2015 |2 20 |o 775 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00775-014-1208-4 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00775-014-1208-4 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Paul |D Lydia |u Departement für Chemie und Biochemie, Universität Bern, 3012, Bern, Switzerland |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Therrien |D Bruno |u Institut de Chimie, Université de Neuchâtel, 2000, Neuchâtel, Switzerland |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Furrer |D Julien |u Departement für Chemie und Biochemie, Universität Bern, 3012, Bern, Switzerland |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t JBIC Journal of Biological Inorganic Chemistry |d Springer Berlin Heidelberg |g 20/1(2015-01-01), 49-59 |x 0949-8257 |q 20:1<49 |1 2015 |2 20 |o 775 | ||