Elemental changes in the hippocampal formation following two different formulas of ketogenic diet: an X-ray fluorescence microscopy study

Verfasser / Beitragende:
[J. Chwiej, A. Patulska, A. Skoczen, K. Janeczko, M. Ciarach, R. Simon, Z. Setkowicz]
Ort, Verlag, Jahr:
2015
Enthalten in:
JBIC Journal of Biological Inorganic Chemistry, 20/8(2015-12-01), 1277-1286
Format:
Artikel (online)
ID: 605507589
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024 7 0 |a 10.1007/s00775-015-1306-y  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00775-015-1306-y 
245 0 0 |a Elemental changes in the hippocampal formation following two different formulas of ketogenic diet: an X-ray fluorescence microscopy study  |h [Elektronische Daten]  |c [J. Chwiej, A. Patulska, A. Skoczen, K. Janeczko, M. Ciarach, R. Simon, Z. Setkowicz] 
520 3 |a The main purpose of the following study was the determination of elemental changes occurring within hippocampal formation as a result of high-fat and carbohydrate-restricted ketogenic diet (KD). To realize it, X-ray fluorescence microscopy was applied for topographic and quantitative analysis of P, S, K, Ca, Fe, Cu, Zn and Se in hippocampal formations taken from rats fed with two different KDs and naive controls. The detailed comparisons were done for sectors 1 and 3 of the Ammon's, the dentate gyrus and hilus of dentate gyrus. The results of elemental analysis showed that the KDs induced statistically significant changes in the accumulation of P, K, Ca, Zn and Se in particular areas of hippocampal formation and these alterations strongly depended on the composition of the diets. Much greater influence on the hippocampal areal densities of examined elements was found for the KD which was characterized by a lower content of carbohydrates, higher content of fats and increased proportion of unsaturated fatty acids. The levels of P, K and Zn decreased whilst those of Ca and Se increased as a result of the treatment with the KDs. 
540 |a The Author(s), 2015 
690 7 |a Ketogenic diet  |2 nationallicence 
690 7 |a Hippocampal formation  |2 nationallicence 
690 7 |a Topographic and quantitative elemental analysis  |2 nationallicence 
690 7 |a X-ray fluorescence microscopy  |2 nationallicence 
690 7 |a Synchrotron radiation  |2 nationallicence 
700 1 |a Chwiej  |D J.  |u Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, Krakow, Poland  |4 aut 
700 1 |a Patulska  |D A.  |u Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, Krakow, Poland  |4 aut 
700 1 |a Skoczen  |D A.  |u Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, Krakow, Poland  |4 aut 
700 1 |a Janeczko  |D K.  |u Institute of Zoology, Jagiellonian University, Krakow, Poland  |4 aut 
700 1 |a Ciarach  |D M.  |u Institute of Zoology, Jagiellonian University, Krakow, Poland  |4 aut 
700 1 |a Simon  |D R.  |u ANKA Synchrotron Radiation Facility, Karlsruhe Institute of Technology, Karlsruhe, Germany  |4 aut 
700 1 |a Setkowicz  |D Z.  |u Institute of Zoology, Jagiellonian University, Krakow, Poland  |4 aut 
773 0 |t JBIC Journal of Biological Inorganic Chemistry  |d Springer Berlin Heidelberg  |g 20/8(2015-12-01), 1277-1286  |x 0949-8257  |q 20:8<1277  |1 2015  |2 20  |o 775 
856 4 0 |u https://doi.org/10.1007/s00775-015-1306-y  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00775-015-1306-y  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chwiej  |D J.  |u Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, Krakow, Poland  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Patulska  |D A.  |u Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, Krakow, Poland  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Skoczen  |D A.  |u Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, Krakow, Poland  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Janeczko  |D K.  |u Institute of Zoology, Jagiellonian University, Krakow, Poland  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ciarach  |D M.  |u Institute of Zoology, Jagiellonian University, Krakow, Poland  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Simon  |D R.  |u ANKA Synchrotron Radiation Facility, Karlsruhe Institute of Technology, Karlsruhe, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Setkowicz  |D Z.  |u Institute of Zoology, Jagiellonian University, Krakow, Poland  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t JBIC Journal of Biological Inorganic Chemistry  |d Springer Berlin Heidelberg  |g 20/8(2015-12-01), 1277-1286  |x 0949-8257  |q 20:8<1277  |1 2015  |2 20  |o 775