The use of a noninvasive hemoglobin monitor for determining fluid distribution and elimination in pediatric patients undergoing minor surgery

Verfasser / Beitragende:
[Qingquan Lian, Husong Li, Ruifeng Zeng, Junhui Lang, Wangning Shangguan, Huacheng Liu, Benfu Wang, Peter Rodhe, Christer Svensen]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Clinical Monitoring and Computing, 29/1(2015-02-01), 41-46
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10877-014-9566-6  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10877-014-9566-6 
245 0 4 |a The use of a noninvasive hemoglobin monitor for determining fluid distribution and elimination in pediatric patients undergoing minor surgery  |h [Elektronische Daten]  |c [Qingquan Lian, Husong Li, Ruifeng Zeng, Junhui Lang, Wangning Shangguan, Huacheng Liu, Benfu Wang, Peter Rodhe, Christer Svensen] 
520 3 |a In pediatric fluid therapy it would be preferable to describe distribution and elimination a fluid bolus based on repetitive hemoglobin (Hb) according to kinetic principles. Pulse CO-Oximetry is a recent advancement in patient monitoring that allows for the continuous noninvasive measurement of Hb (SpHb). The aim of this study was to describe the distribution and elimination of hydroxyethylstarch (HES) 130/0.4 in combination with crystalloids using a noninvasive Hb monitor in two cohorts of young children undergoing minor surgeries under general anesthesia. Two cohorts, 16 children aged 1-3years and 12 aged 4-6years, were investigated during anesthesia and minor surgical procedures. They were given a maintenance solution of lactated Ringer's and a fluid bolus of HES 130/0.4, 6mL/kg over a period of 20min. The whole procedure lasted 120min, and SpHb values were measured every 10min. The SpHb values were used to calculate plasma dilution, net volume, and mean residence time (MRT) of the infused fluid. A total of 377 measured SpHbs generated individual dilution plots that showed variability, particularly for the older cohort. Distribution and elimination rates of the infused fluid were calculated. Mean dilution plots were generated. There were no significant differences in dilution, net volume or MRT between groups. A non invasive Hb analyzer could be used to calculate fluid distribution. The variability in the data can probably be explained by reactions to anesthetic drugs, variability in measurement technique, variability in generating the complex capillary signals, and individual variability in baseline fluid status. The latter finding is important because this is a prerequisite for perioperative fluid planning for each individual. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Fluids  |2 nationallicence 
690 7 |a Fluid therapy  |2 nationallicence 
690 7 |a Fluid distribution  |2 nationallicence 
690 7 |a Fluid elimination  |2 nationallicence 
690 7 |a Pharmacokinetics  |2 nationallicence 
690 7 |a Fluid balance  |2 nationallicence 
700 1 |a Lian  |D Qingquan  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
700 1 |a Li  |D Husong  |u UTMB Health, Galveston, TX, USA  |4 aut 
700 1 |a Zeng  |D Ruifeng  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
700 1 |a Lang  |D Junhui  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
700 1 |a Shangguan  |D Wangning  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
700 1 |a Liu  |D Huacheng  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
700 1 |a Wang  |D Benfu  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
700 1 |a Rodhe  |D Peter  |u Section of Anesthesiology and Intensive Care, Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, 6th Floor, Sjukhusbacken 10, 118 83, Stockholm, Sweden  |4 aut 
700 1 |a Svensen  |D Christer  |u Section of Anesthesiology and Intensive Care, Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, 6th Floor, Sjukhusbacken 10, 118 83, Stockholm, Sweden  |4 aut 
773 0 |t Journal of Clinical Monitoring and Computing  |d Springer Netherlands  |g 29/1(2015-02-01), 41-46  |x 1387-1307  |q 29:1<41  |1 2015  |2 29  |o 10877 
856 4 0 |u https://doi.org/10.1007/s10877-014-9566-6  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10877-014-9566-6  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lian  |D Qingquan  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Li  |D Husong  |u UTMB Health, Galveston, TX, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zeng  |D Ruifeng  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lang  |D Junhui  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shangguan  |D Wangning  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Liu  |D Huacheng  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wang  |D Benfu  |u The Second Hospital and Yuying Children′s Hospital, Wenzhou Medical College, Wenzhou, China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Rodhe  |D Peter  |u Section of Anesthesiology and Intensive Care, Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, 6th Floor, Sjukhusbacken 10, 118 83, Stockholm, Sweden  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Svensen  |D Christer  |u Section of Anesthesiology and Intensive Care, Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, 6th Floor, Sjukhusbacken 10, 118 83, Stockholm, Sweden  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Clinical Monitoring and Computing  |d Springer Netherlands  |g 29/1(2015-02-01), 41-46  |x 1387-1307  |q 29:1<41  |1 2015  |2 29  |o 10877