caa a22 4500 605509654 CHVBK 20210128100642.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10877-014-9564-8 doi (NATIONALLICENCE)springer-10.1007/s10877-014-9564-8 Effect of mild hypocapnia on hemodynamic and bispectral index responses to tracheal intubation during propofol anesthesia in children [Elektronische Daten] [Hyun Kwak, Ji Kim, Kyung Lee, Hong Kim, Jong Kim] The purpose of this study was to investigate the effect of mild hypocapnia on hypertension and arousal response after tracheal intubation in children during propofol anesthesia. Forty-four children, American Society of Anesthesiologists physical status I-II patients, aged 3-9years were randomly allocated to either the normocapnia group [end-tidal carbon dioxide tension (ETCO2=35mmHg, n=22)] or the hypocapnia group (ETCO2=25mmHg, n=22). Anesthesia was induced with propofol 2.5mg/kg. Five minutes after the administration of rocuronium 0.6mg/kg, laryngoscopy was attempted. The mean arterial pressure (MAP), heart rate (HR), SpO2 and bispectral index (BIS) were measured during induction and intubation periods. The maximal change in the BIS with tracheal intubation (ΔBIS) was defined as the difference between the baseline value and the maximal value within the first 5min after intubation. Before tracheal intubation, the change in BIS over time was not different between the groups. After tracheal intubation, the changes in the MAP, HR and BIS over time were not significantly different between the groups. The mean value±SD of ΔBIS was 5.7±5.2 and 7.4±5.5 in the normocapnia and hypocapnia groups, respectively, without any intergroup difference. This study showed that mild hypocapnia did not attenuate hemodynamic and BIS responses to tracheal intubation in children during propofol anesthesia. Our results suggested that hyperventilation has no beneficial effect on hemodynamic and arousal responses to tracheal intubation in children. Springer Science+Business Media New York, 2014 Bispectral index nationallicence Hypocapnia nationallicence Tracheal intubation nationallicence Kwak Hyun Department of Anesthesiology and Pain Medicine, Gil Medical Center, Gachon University, Incheon, Korea aut Kim Ji Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea aut Lee Kyung Department of Anesthesiology and Pain Medicine, Gil Medical Center, Gachon University, Incheon, Korea aut Kim Hong Department of Anesthesiology and Pain Medicine, Gil Medical Center, Gachon University, Incheon, Korea aut Kim Jong Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut Journal of Clinical Monitoring and Computing Springer Netherlands 29/1(2015-02-01), 29-33 1387-1307 29:1<29 2015 29 10877 https://doi.org/10.1007/s10877-014-9564-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10877-014-9564-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kwak Hyun Department of Anesthesiology and Pain Medicine, Gil Medical Center, Gachon University, Incheon, Korea aut NATIONALLICENCE 700 1- Kim Ji Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Lee Kyung Department of Anesthesiology and Pain Medicine, Gil Medical Center, Gachon University, Incheon, Korea aut NATIONALLICENCE 700 1- Kim Hong Department of Anesthesiology and Pain Medicine, Gil Medical Center, Gachon University, Incheon, Korea aut NATIONALLICENCE 700 1- Kim Jong Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, 443-721, Suwon, Korea aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring and Computing Springer Netherlands 29/1(2015-02-01), 29-33 1387-1307 29:1<29 2015 29 10877