caa a22 4500 605509778 CHVBK 20210128100642.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10877-014-9582-6 doi (NATIONALLICENCE)springer-10.1007/s10877-014-9582-6 Accuracy of ultrasound B-lines score and E/Ea ratio to estimate extravascular lung water and its variations in patients with acute respiratory distress syndrome [Elektronische Daten] [Benoît Bataille, Guillaume Rao, Pierre Cocquet, Michel Mora, Bruno Masson, Jean Ginot, Stein Silva, Pierre-Etienne Moussot] Extravascular lung water (EVLW) could increase by permeability pulmonary oedema, cardiogenic oedema, or both. Transthoracic echocardiography examination of a patient allows quantifying B-lines, originating from water-thickened interlobular septa, and the E/Ea ratio, related to pulmonary capillary wedge pressure. The aim of our study was to assess the correlation and the trending ability between EVLW measured by transpulmonary thermodilution and the B-lines score or the E/Ea ratio in patients with ARDS. Twenty-six intensive care unit patients were prospectively included. B-lines score was obtained from four ultrasound zones (anterior and lateral chest on left and right hemithorax). E/Ea was measured from the apical four-chamber view. EVLW was compared with the B-lines score and the E/Ea ratio. A linear mixed effect model was used to take account the repeated measurements. A p value <0.05 was considered significant. A total of 73 measurements were collected. The correlation coefficient between EVLW and B-lines score was 0.66 (EVLW=0.71 B-lines+7.64, R2=0.44, p=0.001), versus 0.31 for E/Ea (p=0.06). The correlation between EVLW changes and B-lines variations was significant (R2=0.26, p<0.01), with a concordance rate of 74%. A B-lines score ≥6 had a sensitivity of 82% and a specificity of 77% to predict EVLW >10ml/kg, with an AUC equal to 0.86 (0.76-0.93). The gray zone approach identified a range of B-lines between four and seven for which EVLW >10ml/kg could not be predicted reliably. The correlation between ultrasound B-lines and EVLW was significant, but the B-lines score was not able to track EVLW changes reliably. Springer Science+Business Media New York, 2014 Measurement techniques—thermodilution nationallicence Measurement techniques—Doppler echocardiography nationallicence Lung—adult respiratory distress syndrome nationallicence Heart—myocardial function nationallicence Bataille Benoît Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut Rao Guillaume Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut Cocquet Pierre Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut Mora Michel Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut Masson Bruno Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut Ginot Jean Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut Silva Stein Pôle d'Anesthésie-Réanimation, Centre Hospitalier Universitaire, CHU Purpan, Place du Dr Baylac, 31059, Toulouse Cedex 9, France aut Moussot Pierre-Etienne Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut Journal of Clinical Monitoring and Computing Springer Netherlands 29/1(2015-02-01), 169-176 1387-1307 29:1<169 2015 29 10877 https://doi.org/10.1007/s10877-014-9582-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10877-014-9582-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bataille Benoît Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut NATIONALLICENCE 700 1- Rao Guillaume Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut NATIONALLICENCE 700 1- Cocquet Pierre Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut NATIONALLICENCE 700 1- Mora Michel Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut NATIONALLICENCE 700 1- Masson Bruno Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut NATIONALLICENCE 700 1- Ginot Jean Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut NATIONALLICENCE 700 1- Silva Stein Pôle d'Anesthésie-Réanimation, Centre Hospitalier Universitaire, CHU Purpan, Place du Dr Baylac, 31059, Toulouse Cedex 9, France aut NATIONALLICENCE 700 1- Moussot Pierre-Etienne Service de Réanimation Polyvalente, Centre Hospitalier de Narbonne, Bd Dr Lacroix, 11100, Narbonne, France aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring and Computing Springer Netherlands 29/1(2015-02-01), 169-176 1387-1307 29:1<169 2015 29 10877