Early monitoring of ventriculostomy-related infections with procalcitonin in patients with ventricular drains
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| 024 | 7 | 0 | |a 10.1007/s10877-015-9663-1 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10877-015-9663-1 | ||
| 245 | 0 | 0 | |a Early monitoring of ventriculostomy-related infections with procalcitonin in patients with ventricular drains |h [Elektronische Daten] |c [Amr Omar, Amr ElShawarby, Rajvir Singh] |
| 520 | 3 | |a Several factors are implicated in the increased vulnerability of multiple trauma victims to infection, especially in intensive care units. The incidence of EVD related infections ranges from 5 to 20%. To assess the accuracy of serum procalcitonin (PCT) in predicting central nervous system (CNS) infection in patients with EVDs. Thirty-six adult patients with severe head trauma were enrolled in this prospective study, after exclusion of other causes of fever; patients were subjected to sampling of C-reactive protein (CRP), PCT, and cerebrospinal fluid (CSF) cultures every other day. Five patients developed ventriculostomy-related infections, and all had an elevated serum PCT concentration. Patients with negative CSF cultures had mean serum PCT <2.0ng/ml, while patients with positive culture had early elevation of serum PCT with mean of 4.18ng/ml, CRP did not show similar early changes. Patients who acquire CNS infection had prolonged length of stay in hospital and length of ventilation. In absence of other nosocomial infections, early high serum PCT concentrations appear to be a reliable indicator of bacterial CNS infection in patients with EVD. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Procacitonin |2 nationallicence | |
| 690 | 7 | |a External ventricular drain |2 nationallicence | |
| 690 | 7 | |a Meningitis |2 nationallicence | |
| 690 | 7 | |a APACHE II : Acute physiology and chronic health evaluation score II |2 nationallicence | |
| 690 | 7 | |a CDC : Centers for Disease Control and Prevention |2 nationallicence | |
| 690 | 7 | |a CNS : Central nervous system |2 nationallicence | |
| 690 | 7 | |a CSF : Cerebrospinal fluid |2 nationallicence | |
| 690 | 7 | |a CRP : C-reactive protein |2 nationallicence | |
| 690 | 7 | |a DC : Decompressive craniectomy |2 nationallicence | |
| 690 | 7 | |a ECL : Electrochemiluminescence |2 nationallicence | |
| 690 | 7 | |a EVD : External ventricular drain |2 nationallicence | |
| 690 | 7 | |a GCS : Glasgow coma scale |2 nationallicence | |
| 690 | 7 | |a ICP : Intracranial pressure |2 nationallicence | |
| 690 | 7 | |a ICU : Intensive care unit |2 nationallicence | |
| 690 | 7 | |a ICULOS : Length of stay in ICU |2 nationallicence | |
| 690 | 7 | |a ICULOV : Length of ventilation in ICU |2 nationallicence | |
| 690 | 7 | |a MRSA : Methicillin-resistant staphylococcus aureus |2 nationallicence | |
| 690 | 7 | |a PCT : Procalcitonin |2 nationallicence | |
| 690 | 7 | |a Tmax : Maximum temperature |2 nationallicence | |
| 690 | 7 | |a WBC : White blood cell count |2 nationallicence | |
| 700 | 1 | |a Omar |D Amr |u Department of Cardiothoracic Surgery/Cardiac Anaesthesia & ICU Section, Heart Hospital, Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar |4 aut | |
| 700 | 1 | |a ElShawarby |D Amr |u Tawam Hospital, Abu Dhabi, UAE |4 aut | |
| 700 | 1 | |a Singh |D Rajvir |u Biostatistics, Medial Research Department, Hamad Medical Corporation, Doha, Qatar |4 aut | |
| 773 | 0 | |t Journal of Clinical Monitoring and Computing |d Springer Netherlands |g 29/6(2015-12-01), 759-765 |x 1387-1307 |q 29:6<759 |1 2015 |2 29 |o 10877 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10877-015-9663-1 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10877-015-9663-1 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Omar |D Amr |u Department of Cardiothoracic Surgery/Cardiac Anaesthesia & ICU Section, Heart Hospital, Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a ElShawarby |D Amr |u Tawam Hospital, Abu Dhabi, UAE |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Singh |D Rajvir |u Biostatistics, Medial Research Department, Hamad Medical Corporation, Doha, Qatar |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Clinical Monitoring and Computing |d Springer Netherlands |g 29/6(2015-12-01), 759-765 |x 1387-1307 |q 29:6<759 |1 2015 |2 29 |o 10877 | ||