Accuracy of the transpulmonary ultrasound dilution method for detection of small anatomic shunts
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| 024 | 7 | 0 | |a 10.1007/s10877-014-9618-y |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10877-014-9618-y | ||
| 245 | 0 | 0 | |a Accuracy of the transpulmonary ultrasound dilution method for detection of small anatomic shunts |h [Elektronische Daten] |c [R. Saxena, N. Krivitski, K. Peacock, A. Durward, J. Simpson, S. Tibby] |
| 520 | 3 | |a The purpose of this study wasto investigate the qualitative and quantitative accuracy of transpulmonary ultrasound dilution (UD) (COstatus™, Transonic Systems) for the detection of small anatomic shunts. It was a prospective, observational study in a multi-disciplinary pediatric intensive care unit. Seventy-three critically ill children (67 post cardiac surgery), with a median (IQR) age of 10 (3-50.3)months and a median (IQR) weight of 8 (3.43-13)kg were enrolled. Ultrasound dilution (UD) measurements were performed on patients within 1h of undergoing two-dimensional echocardiography, which was used as the comparator technique. Shunt was diagnosed by characteristic changes on the UD curve shape, and was considered "test-positive” only if two or more measurements suggested the presence of the shunt. The UD technology also provided an estimate of pulmonaryto systemic blood flow ratio (Qp:Qs). 12/73 (16.4%) patients had a shunt identified by both UD and echocardiography. The overall accuracy (95% CI) was 86.1% (75.6-96.6%), with a sensitivity of 85.7% (57.2-98.2%) and specificity of 86.4% (75.0-94.0%). The estimated Qp:Qs ranged from 0.7 to 1.4, which was consistent qualitatively with the echocardiographic findings on color flowdoppler. Shunt was detected by UD alone in eight children; six of these had clinical conditions known to compromise dilution curve analysis (valve regurgitation, asymmetric pulmonary blood flow). Shunt was detected by echocardiography alone in two children; in both cases the shunt was tiny. UD is an accurate method for the detection of small anatomical shunts, both qualitatively and quantitatively. | |
| 540 | |a Springer Science+Business Media New York, 2014 | ||
| 690 | 7 | |a Ultrasound dilution |2 nationallicence | |
| 690 | 7 | |a Echocardiography |2 nationallicence | |
| 690 | 7 | |a Shunt detection |2 nationallicence | |
| 700 | 1 | |a Saxena |D R. |u Paediatric Intensive Care Unit, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | |
| 700 | 1 | |a Krivitski |D N. |u Transonic Systems Inc, 34 Dutch Mill Road, 14850, Ithaca, NY, USA |4 aut | |
| 700 | 1 | |a Peacock |D K. |u Department of Paediatric Cardiology, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | |
| 700 | 1 | |a Durward |D A. |u Paediatric Intensive Care Unit, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | |
| 700 | 1 | |a Simpson |D J. |u Department of Paediatric Cardiology, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | |
| 700 | 1 | |a Tibby |D S. |u Paediatric Intensive Care Unit, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | |
| 773 | 0 | |t Journal of Clinical Monitoring and Computing |d Springer Netherlands |g 29/3(2015-06-01), 407-414 |x 1387-1307 |q 29:3<407 |1 2015 |2 29 |o 10877 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10877-014-9618-y |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10877-014-9618-y |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Saxena |D R. |u Paediatric Intensive Care Unit, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Krivitski |D N. |u Transonic Systems Inc, 34 Dutch Mill Road, 14850, Ithaca, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Peacock |D K. |u Department of Paediatric Cardiology, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Durward |D A. |u Paediatric Intensive Care Unit, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Simpson |D J. |u Department of Paediatric Cardiology, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tibby |D S. |u Paediatric Intensive Care Unit, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London, UK |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Clinical Monitoring and Computing |d Springer Netherlands |g 29/3(2015-06-01), 407-414 |x 1387-1307 |q 29:3<407 |1 2015 |2 29 |o 10877 | ||