caa a22 4500 605510288 CHVBK 20210128100645.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10877-014-9642-y doi (NATIONALLICENCE)springer-10.1007/s10877-014-9642-y Utility of near infrared light to determine tissue oxygenation during hepato-biliary surgery [Elektronische Daten] [N. Murphy, S. Fröhlich, T. Kong, J. Boylan, N. Conlon] Near-infrared spectrophotometry assesses cerebral oxygen saturation (ScO2) based on the absorption spectra of oxygenated and deoxygenated hemoglobin, and the translucency of biological tissue, in the near-infrared band. There is increasing evidence that optimising cerebral oxygenation, guided by ScO2, is associated with improved outcomes in a variety of high risk surgical settings. However, in patients with liver disease, bilirubin can potentially render cerebral oximetry inaccurate. As a result, measurement of cerebral oxygen saturation is rarely undertaken in patients undergoing hepatobiliary surgery. We prospectively measured baseline and intraoperative cerebral oxygen saturation in patients undergoing major pancreatic surgery. Indices including bilirubin, sodium, platelets and maximum amplitude on thromboelastography were associated with low baseline ScO2. However, those patients with low ScO2 (≤51%) maintained a similar trend in cerebral oximetry values both at induction and intraoperatively to those with a normal ScO2. We conclude that the pattern of cerebral oximetry is similar in patients undergoing major pancreatic surgery regardless of their underlying liver dysfunction. Therefore, cerebral oximetry may have a role in monitoring neurological function in this high risk group of patients. Springer Science+Business Media New York, 2014 Cerebral oximetry nationallicence Bilirubin nationallicence Liver nationallicence Hepatobiliary nationallicence Murphy N. Department of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland aut Fröhlich S. Department of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland aut Kong T. Department of Anaesthesia and Intensive Care Medicine, Galway University Hospital, Galway, Ireland aut Boylan J. Department of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland aut Conlon N. Department of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland aut Journal of Clinical Monitoring and Computing Springer Netherlands 29/5(2015-10-01), 613-619 1387-1307 29:5<613 2015 29 10877 https://doi.org/10.1007/s10877-014-9642-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10877-014-9642-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Murphy N. Department of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland aut NATIONALLICENCE 700 1- Fröhlich S. Department of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland aut NATIONALLICENCE 700 1- Kong T. Department of Anaesthesia and Intensive Care Medicine, Galway University Hospital, Galway, Ireland aut NATIONALLICENCE 700 1- Boylan J. Department of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland aut NATIONALLICENCE 700 1- Conlon N. Department of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring and Computing Springer Netherlands 29/5(2015-10-01), 613-619 1387-1307 29:5<613 2015 29 10877