caa a22 4500 605510342 CHVBK 20210128100645.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10877-014-9643-x doi (NATIONALLICENCE)springer-10.1007/s10877-014-9643-x Change in auditory evoked potential index and bispectral index during induction of anesthesia with anesthetic drugs [Elektronische Daten] [Sachiko Matsushita, Shinya Oda, Kei Otaki, Masaki Nakane, Kaneyuki Kawamae] The aim of this study was to evaluate the efficacy of the auditory evoked potential (AEP) index (aepEX) as an assessment tool for hypnosis during induction of various anesthetic drugs, and to compare its performance to that of the bispectral index (BIS). A total of 45 cases were divided into three groups based on the drugs used for anesthesia. Before anesthetic induction, BIS and AEP monitors were initiated. Anesthesia was induced through intravenous injection (IV) as follows: MP (n=15) group, midazolam (0.1mg/kg IV); TP (n=15) group, thiopental (4mg/kg IV); and KP (n=15) group, ketamine (2mg/kg IV). After loss of response (LOR), an infusion of 3μg/ml propofol via a target-controlled infusion was initiated in all groups. AepEX and BIS were measured in the waking state (baseline) and at LOR (1min after LOR), pre-intubation (1min after previous intubation) and post-intubation (1min after tracheal intubation finished). The value of aepEX significantly decreased in all groups with LOR and that of BIS also decreased except of KP group. No significant difference were observed in BIS values between baseline and LOR in the KS group. The aepEX might be more useful than BIS for hypnosis monitoring during anesthetic induction, particularly when drugs such as ketamine are used. The Author(s), 2014 Auditory evoked potential nationallicence Bispectral index nationallicence Depth of anesthesia monitors nationallicence Matsushita Sachiko Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut Oda Shinya Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut Otaki Kei Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut Nakane Masaki Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut Kawamae Kaneyuki Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut Journal of Clinical Monitoring and Computing Springer Netherlands 29/5(2015-10-01), 621-626 1387-1307 29:5<621 2015 29 10877 https://doi.org/10.1007/s10877-014-9643-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10877-014-9643-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Matsushita Sachiko Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut NATIONALLICENCE 700 1- Oda Shinya Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut NATIONALLICENCE 700 1- Otaki Kei Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut NATIONALLICENCE 700 1- Nakane Masaki Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut NATIONALLICENCE 700 1- Kawamae Kaneyuki Department of Anesthesiology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-2323, Yamagata, Japan aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring and Computing Springer Netherlands 29/5(2015-10-01), 621-626 1387-1307 29:5<621 2015 29 10877