Noninvasive assessment of peripheral microcirculation by near-infrared spectroscopy: a comparative study in healthy smoking and nonsmoking volunteers

Verfasser / Beitragende:
[Guillaume Zamparini, Géraldine Butin, Marc-Olivier Fischer, Jean-Louis Gérard, Jean-Luc Hanouz, Jean-Luc Fellahi]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Clinical Monitoring and Computing, 29/5(2015-10-01), 555-559
Format:
Artikel (online)
ID: 605510369
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024 7 0 |a 10.1007/s10877-014-9631-1  |2 doi 
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245 0 0 |a Noninvasive assessment of peripheral microcirculation by near-infrared spectroscopy: a comparative study in healthy smoking and nonsmoking volunteers  |h [Elektronische Daten]  |c [Guillaume Zamparini, Géraldine Butin, Marc-Olivier Fischer, Jean-Louis Gérard, Jean-Luc Hanouz, Jean-Luc Fellahi] 
520 3 |a Smokers are exposed to early endothelial dysfunction. This microcirculatory damage can be demonstrated by near-infrared spectroscopy (NIRS). The aim of this study was to compare microvascular reactivity by NIRS during a dynamic vascular occlusion test in healthy smokers and nonsmokers volunteers. Twenty healthy volunteers (10 men, 10 women), aged from 22 to 38years old, were included after approval of the local Ethics Committee and divided into two groups: smokers (n=10) and nonsmokers (n=10). Tissue oxygen saturation (StO2) was measured at the level of each individual's calves during an ischemia and reperfusion test. In addition, during the ischemia phase, the slope of decline in StO2 was determined. Therefore, for each group, we were able to deduce the speed of desaturation (ΔStO2/ischemia time). The same was applied for resaturation rates during the reperfusion phase (ΔStO2/reperfusion time). StO2 values were comparable at all experimental steps between smokers and nonsmokers. During the vascular occlusion test, rates of desaturation were the same between smokers and nonsmokers [respectively 3.7%·min−1 (range 2.5-12.6) and 3.7%·min−1 (range 1.8-15.1); p=0.50]. It was the same for the rate of resaturation [smokers 30.4%·min−1 (range 14.2-51.6) and nonsmokers 30.5%·min−1 (range 18.6-44.5); p=0.82]. NIRS study of microvascular reactivity during a dynamic vascular occlusion test did not reveal any difference between smokers and nonsmokers. Therefore, NIRS could not be sensitive enough to highlight endothelial dysfunction in healthy subjects exposed to tobacco smoke. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Near-infrared spectroscopy  |2 nationallicence 
690 7 |a Vascular occlusion test  |2 nationallicence 
690 7 |a Microcirculatory  |2 nationallicence 
690 7 |a Tobacco  |2 nationallicence 
700 1 |a Zamparini  |D Guillaume  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
700 1 |a Butin  |D Géraldine  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
700 1 |a Fischer  |D Marc-Olivier  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
700 1 |a Gérard  |D Jean-Louis  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
700 1 |a Hanouz  |D Jean-Luc  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
700 1 |a Fellahi  |D Jean-Luc  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
773 0 |t Journal of Clinical Monitoring and Computing  |d Springer Netherlands  |g 29/5(2015-10-01), 555-559  |x 1387-1307  |q 29:5<555  |1 2015  |2 29  |o 10877 
856 4 0 |u https://doi.org/10.1007/s10877-014-9631-1  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zamparini  |D Guillaume  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Butin  |D Géraldine  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fischer  |D Marc-Olivier  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Gérard  |D Jean-Louis  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hanouz  |D Jean-Luc  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fellahi  |D Jean-Luc  |u Department of Anesthesiology and Critical Care Medicine, Pôle Réanimations Anesthésie SAMU, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Clinical Monitoring and Computing  |d Springer Netherlands  |g 29/5(2015-10-01), 555-559  |x 1387-1307  |q 29:5<555  |1 2015  |2 29  |o 10877