caa a22 4500 605510474 CHVBK 20210128100646.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10877-014-9596-0 doi (NATIONALLICENCE)springer-10.1007/s10877-014-9596-0 The evaluation of a non-invasive respiratory volume monitor in surgical patients undergoing elective surgery with general anesthesia [Elektronische Daten] [Christopher Voscopoulos, C. MacNabb, Jordan Brayanov, Lizeng Qin, Jenny Freeman, Gary Mullen, Diane Ladd, Edward George] Continuous respiratory assessment is especially important during post-operative care following extubation. Respiratory depression and subsequent adverse outcomes can arise due to opioid administration and/or residual anesthetics. A non-invasive respiratory volume monitor (RVM) has been developed that provides continuous, real-time, measurements of minute ventilation (MV), tidal volume (TV), and respiratory rate (RR) via a standardized set of thoracic electrodes. Previous work demonstrated accuracy of the RVM versus standard spirometry and its utility in demonstrating response to opioids in postoperative patients. This study evaluated the correlation between RVM measurements of MV, TV and RR to ventilator measurements during general anesthesia (GA). Continuous digital RVM and ventilator traces, as well as RVM measurements of MV, TV and RR, were analyzed from ten patients (mean 62.6±7.4years; body mass index 28.6±5.2kg/m2) undergoing surgery with GA. RVM data were compared to ventilator data and bias, precision and accuracy were calculated. The average MV difference between the RVM and ventilator was −0.10L/min (bias: −1.3%, precision: 6.6%, accuracy: 9.0%. The average TV difference was 40mL (bias: 0.4%, precision: 7.3%, accuracy: 9.1%). The average RR difference was −0.22 breaths/minute (bias: −1.8%, precision: 3.7% accuracy: 4.1%). Correlations between the RVM traces and the ventilator were compared at various points with correlations >0.90 throughout. Pairing the close correlation to ventilator measurements in intubated patients demonstrated by this study with previously described accuracy compared to spirometry in non-intubated patients, the RVM can be considered to have the capability to provide continuity of ventilation monitoring post-extubation This supports the use of real-time continuous RVM measurements to drive post-operative and post-extubation protocols, initiate therapeutic interventions and improve patient safety. Springer Science+Business Media New York, 2014 Non-invasive respiratory volume monitoring nationallicence Thoracic bio-impedance nationallicence General anesthesia nationallicence Ventilation monitoring in non-intubated patients nationallicence Voscopoulos Christopher Department of Anesthesiology, Pain and Perioperative Medicine, Brigham and Woman's Hospital, Harvard Medical School, Boston, MA, USA aut MacNabb C. Respiratory Motion, Inc., 411 Waverley Oaks Road, Suite 150, 02452, Waltham, MA, USA aut Brayanov Jordan Respiratory Motion, Inc., 411 Waverley Oaks Road, Suite 150, 02452, Waltham, MA, USA aut Qin Lizeng Harvard Medical School, Boston, MA, USA aut Freeman Jenny Respiratory Motion, Inc., 411 Waverley Oaks Road, Suite 150, 02452, Waltham, MA, USA aut Mullen Gary East Carolina Anesthesia Associates, PLLC, Greenville, NC, USA aut Ladd Diane Respiratory Motion, Inc., 411 Waverley Oaks Road, Suite 150, 02452, Waltham, MA, USA aut George Edward Department of Anesthesia, Massachesetts General Hospital, Harvard Medical School, Boston, MA, USA aut Journal of Clinical Monitoring and Computing Springer Netherlands 29/2(2015-04-01), 223-230 1387-1307 29:2<223 2015 29 10877 https://doi.org/10.1007/s10877-014-9596-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10877-014-9596-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Voscopoulos Christopher Department of Anesthesiology, Pain and Perioperative Medicine, Brigham and Woman's Hospital, Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- MacNabb C. Respiratory Motion, Inc., 411 Waverley Oaks Road, Suite 150, 02452, Waltham, MA, USA aut NATIONALLICENCE 700 1- Brayanov Jordan Respiratory Motion, Inc., 411 Waverley Oaks Road, Suite 150, 02452, Waltham, MA, USA aut NATIONALLICENCE 700 1- Qin Lizeng Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- Freeman Jenny Respiratory Motion, Inc., 411 Waverley Oaks Road, Suite 150, 02452, Waltham, MA, USA aut NATIONALLICENCE 700 1- Mullen Gary East Carolina Anesthesia Associates, PLLC, Greenville, NC, USA aut NATIONALLICENCE 700 1- Ladd Diane Respiratory Motion, Inc., 411 Waverley Oaks Road, Suite 150, 02452, Waltham, MA, USA aut NATIONALLICENCE 700 1- George Edward Department of Anesthesia, Massachesetts General Hospital, Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring and Computing Springer Netherlands 29/2(2015-04-01), 223-230 1387-1307 29:2<223 2015 29 10877