caa a22 4500 605510482 CHVBK 20210128100646.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10877-014-9606-2 doi (NATIONALLICENCE)springer-10.1007/s10877-014-9606-2 Estimation of shunt fraction by transesophageal echocardiography during one-lung ventilation [Elektronische Daten] [Miao Wang, Quan Gong, Wei Wei] As the blood flow volume in non-dependent lung composed the primary part of the intrapulmonary shunt during one-lung ventilation (OLV), the shunt fraction (SF) during OLV can be represented by the ratio of blood flow volume in non-dependent lung to the bilateral lung. The purpose of this study is to estimate the shunt in non-dependent lung by transesophageal echocardiography (TEE). Fifteen adult patients requiring OLV for thoracic surgery were enrolled in the study. The upper pulmonary venous flow pattern in bilateral lung and main pulmonary artery flow pattern were acquired respectively by TEE for their velocity time integral (VTI) measurements in following time intervals: before OLV (T0), 30min after OLV (T30) and 60min after OLV (T60). Simultaneously the arterial blood was sampled for gas analysis. SF was calculated by VTI of bilateral upper pulmonary veins, and percentage change of blood flow (BFP) was the ratio of upper pulmonary venous VTI between in OLV period and before OLV in non-dependent lung. There was significant decrease in PaO2 and increase in cardiac output after OLV. The pulmonary blood flow in non-dependent lung decreased significantly compared with T0, and SF was 37.1±8.3 and 35.2±7.2% respectively at T30 and T60. There was significant liner correlation between SF and PaO2 (r=0.717), and between BFP and PaO2 (r=0.593). It is feasible to estimate intrapulmonary shunt by TEE in anesthetized patients undergoing OLV. SF measured by TEE has significant correlation with PaO2, and it wouldexpected to be used to predict hypoxemia during OLV. Springer Science+Business Media New York, 2014 Transesophageal echocardiography nationallicence Shunt fraction nationallicence Pulmonary blood flow nationallicence One-lung ventilation nationallicence Wang Miao Department of Anesthesiology, West China Hospital, Sichuan University, No 37, Guo-xue-xiang Street, 610041, Chengdu, Sichuan, China aut Gong Quan Department of Orthopedics, West China Hospital, Sichuan University, 610041, Chengdu, Sichuan, China aut Wei Wei Department of Anesthesiology, West China Hospital, Sichuan University, No 37, Guo-xue-xiang Street, 610041, Chengdu, Sichuan, China aut Journal of Clinical Monitoring and Computing Springer Netherlands 29/2(2015-04-01), 307-311 1387-1307 29:2<307 2015 29 10877 https://doi.org/10.1007/s10877-014-9606-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10877-014-9606-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Miao Department of Anesthesiology, West China Hospital, Sichuan University, No 37, Guo-xue-xiang Street, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Gong Quan Department of Orthopedics, West China Hospital, Sichuan University, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Wei Wei Department of Anesthesiology, West China Hospital, Sichuan University, No 37, Guo-xue-xiang Street, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring and Computing Springer Netherlands 29/2(2015-04-01), 307-311 1387-1307 29:2<307 2015 29 10877