Parental environmental exposure leads to glycometabolic disturbances that affect fertilization of eggs in the silkworm Bombyx mori
the parental transcript legacy
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 605513937 | ||
| 003 | CHVBK | ||
| 005 | 20210128100702.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20150101xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00360-014-0864-6 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00360-014-0864-6 | ||
| 245 | 0 | 0 | |a Parental environmental exposure leads to glycometabolic disturbances that affect fertilization of eggs in the silkworm Bombyx mori |h [Elektronische Daten] |b the parental transcript legacy |c [H. Tao, H. Liu, Y. Cheng, Y. Sima, W. Yin, S. Xu] |
| 520 | 3 | |a Parental transcript legacy plays an important role in fertilization and development of the early embryo. Parental environmental exposure affects the fertilization of eggs, but the underlying biochemical mechanism is largely unresolved. In this study, the parental environmental effects on fertilization of eggs were explored in the silkworm Bombyx mori (B. mori), an ideal lepidopteran animal model. The results showed that the rate of fertilization decreased after the parents were exposed to a poor environment at 32°C with continuous illumination for 72h on days 6-9 of the pupal stage, which is a key period for germ cell maturation. This was likely attributable to lower energy charge values, obstructed nicotinamide adenine dinucleotide (NAD+) regeneration and inactive tricarboxylic acid cycle (TCA), leading to accumulation of large amounts of pyruvic acid and lactic acid. This effect was related to energy metabolism via glycolysis; in particular disruption of pyruvate metabolism. In conclusion, this study showed parental exposure to an abnormal environment during germ cell maturation affected glycolysis and the subsequent fertilization of eggs via the parental transcript legacy in B. mori. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2014 | ||
| 690 | 7 | |a Bombyx mori |2 nationallicence | |
| 690 | 7 | |a Fertilization |2 nationallicence | |
| 690 | 7 | |a Glycolysis |2 nationallicence | |
| 690 | 7 | |a Environmental exposure |2 nationallicence | |
| 690 | 7 | |a Parental transcript legacy |2 nationallicence | |
| 690 | 7 | |a 25LD : 12-hours light-dark cycles at 25°C |2 nationallicence | |
| 690 | 7 | |a 32LL : Constant illumination at 32°C |2 nationallicence | |
| 690 | 7 | |a DEM : Disorders of energy metabolism |2 nationallicence | |
| 690 | 7 | |a E0 : Eggs from virgin females |2 nationallicence | |
| 690 | 7 | |a E1-E3 : Eggs collected at 1-3h after oviposition |2 nationallicence | |
| 700 | 1 | |a Tao |D H. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | |
| 700 | 1 | |a Liu |D H. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | |
| 700 | 1 | |a Cheng |D Y. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | |
| 700 | 1 | |a Sima |D Y. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | |
| 700 | 1 | |a Yin |D W. |u Institute for Cardiovascular Science, Soochow University, 215123, Suzhou, China |4 aut | |
| 700 | 1 | |a Xu |D S. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | |
| 773 | 0 | |t Journal of Comparative Physiology B |d Springer Berlin Heidelberg |g 185/1(2015-01-01), 47-55 |x 0174-1578 |q 185:1<47 |1 2015 |2 185 |o 360 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00360-014-0864-6 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00360-014-0864-6 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tao |D H. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Liu |D H. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cheng |D Y. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sima |D Y. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yin |D W. |u Institute for Cardiovascular Science, Soochow University, 215123, Suzhou, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Xu |D S. |u Department of Applied Biology, School of Biology and Basic Medical Sciences, Soochow University, 215123, Suzhou, China |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Comparative Physiology B |d Springer Berlin Heidelberg |g 185/1(2015-01-01), 47-55 |x 0174-1578 |q 185:1<47 |1 2015 |2 185 |o 360 | ||