caa a22 4500 60551397X CHVBK 20210128100702.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00360-014-0851-y doi (NATIONALLICENCE)springer-10.1007/s00360-014-0851-y Trypsin isozymes in the lobster Panulirus argus (Latreille, 1804): from molecules to physiology [Elektronische Daten] [Erick Perera, Leandro Rodríguez-Viera, Rolando Perdomo-Morales, Vivian Montero-Alejo, Francisco Moyano, Gonzalo Martínez-Rodríguez, Juan Mancera] Trypsin enzymes have been studied in a wide variety of animal taxa due to their central role in protein digestion as well as in other important physiological and biotechnological processes. Crustacean trypsins exhibit a high number of isoforms. However, while differences in properties of isoenzymes are known to play important roles in regulating different physiological processes, there is little information on this aspect for decapod trypsins. The aim of this review is to integrate recent findings at the molecular level on trypsin enzymes of the spiny lobster Panulirus argus, into higher levels of organization (biochemical, organism) and to interpret those findings in relation to the feeding ecology of these crustaceans. Trypsin in lobster is a polymorphic enzyme, showing isoforms that differ in their biochemical features and catalytic efficiencies. Molecular studies suggest that polymorphism in lobster trypsins may be non-neutral. Trypsin isoenzymes are differentially regulated by dietary proteins, and it seems that some isoenzymes have undergone adaptive evolution coupled with a divergence in expression rate to increase fitness. This review highlights important but poorly studied issues in crustaceans in general, such as the relation among trypsin polymorphism, phenotypic (digestive) flexibility, digestion efficiency, and feeding ecology. Springer-Verlag Berlin Heidelberg, 2014 Digestion biochemistry nationallicence Ecological physiology nationallicence Panulirus argus nationallicence Protein digestion nationallicence Trypsin polymorphism nationallicence Spiny lobster nationallicence Perera Erick Center for Marine Research, University of Havana, Havana, Cuba aut Rodríguez-Viera Leandro Center for Marine Research, University of Havana, Havana, Cuba aut Perdomo-Morales Rolando Biochemistry Department, Center for Pharmaceuticals Research and Development, Havana, Cuba aut Montero-Alejo Vivian Biochemistry Department, Center for Pharmaceuticals Research and Development, Havana, Cuba aut Moyano Francisco Department of Applied Biology, University of Almeria, Almería, Spain aut Martínez-Rodríguez Gonzalo ICMAN-CSIC, Apartado Oficial, 11510, Puerto Real, Cádiz, Spain aut Mancera Juan Department of Biology, Faculty of Marine and Environmental Science, University of Cadiz, Cádiz, Spain aut Journal of Comparative Physiology B Springer Berlin Heidelberg 185/1(2015-01-01), 17-35 0174-1578 185:1<17 2015 185 360 https://doi.org/10.1007/s00360-014-0851-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00360-014-0851-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Perera Erick Center for Marine Research, University of Havana, Havana, Cuba aut NATIONALLICENCE 700 1- Rodríguez-Viera Leandro Center for Marine Research, University of Havana, Havana, Cuba aut NATIONALLICENCE 700 1- Perdomo-Morales Rolando Biochemistry Department, Center for Pharmaceuticals Research and Development, Havana, Cuba aut NATIONALLICENCE 700 1- Montero-Alejo Vivian Biochemistry Department, Center for Pharmaceuticals Research and Development, Havana, Cuba aut NATIONALLICENCE 700 1- Moyano Francisco Department of Applied Biology, University of Almeria, Almería, Spain aut NATIONALLICENCE 700 1- Martínez-Rodríguez Gonzalo ICMAN-CSIC, Apartado Oficial, 11510, Puerto Real, Cádiz, Spain aut NATIONALLICENCE 700 1- Mancera Juan Department of Biology, Faculty of Marine and Environmental Science, University of Cadiz, Cádiz, Spain aut NATIONALLICENCE 773 0- Journal of Comparative Physiology B Springer Berlin Heidelberg 185/1(2015-01-01), 17-35 0174-1578 185:1<17 2015 185 360